Genomic Organization
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| What are the three sequence classes of genomes | Highly Repetitive,Intermediate, Rare
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| This genome class has up to a million copies per genome | Highly repetitive
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| This genome class has a hundred to thousands of copies per genome | Intermediate
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| This genome class has usually one copy per genome | Rare
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| This genome class does not usually encode genes. Its function is structural | Highly repetitive
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| A repeat of a genome with the same sequence over and over, end to end | Tandem array
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| The majority of this genome class are degenerate transposons, particularly retrotransposons | Intermediate
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| Sequences capable of moving from one location in the genome to another | Transposons
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| Parasitic DNA molecules capable of moving from once cell to another with the use of an RNA intermediate | Retroviruses
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| One of the most abundant transposable elementes in our genome | Alu sequences
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| rRNAs, 5S-rRNA, tRNAs and histones are functional genes belonging to what class of genome | Intermediate
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| How are intermediate class gens usually arranged | In clusters
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| The largest of the three classes of genomes | Rare
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| Most functional gene belong to this class of genome | Rare
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| Groups of gene which are classified together because they have regions with similar, but not necessarily identical sequences | Gene Families
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| Gene family members are beleived to be ..., which means they evolved from a common ancestral gene | Homologous
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| An estimate of how closely related gens are based on sequence similarity | Homology
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| The regions where there is very little change in sequence between homologous genes | Conserved domains
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| The most common bases (or residue) at each position on a sequence analysis | Consensus sequence
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| Gene families that are group closely together on the chromosome. They differ from tandem repeats because they are not identical, not as contigous, and the gens are not necessarily oriented in the same direction | Clustered gene families
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| Geneomic sequences similar to expressed genes, but which have been mutated so they no longer express a gene product | Pseudogenes
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| A clinical condition where fetal gamma globin expression persists throughout life. | Hereditary persistnece of fetal hemoglobin
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| Defective alpha or beta globins. With severe cases, red blood cells die in bone marrow resulting in thinned bone cortex, fractures and distoriton s of the head, marked enlargement of liver and spleen and death within a decade. | Thalassemias
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