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viral Diseases of the Skin

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Question
Answer
gingivostomatitis   oral lesions caused by Herpes Simplex Virus I--lesions around and in much of the mouth--spread by direct contact--virus becomes latent in neurons that innervate face/mouth--only 1-2 blisters on reactivation--stress, ultraviolet light, some cosmetics, etc.  
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Herpes labialis   cold sores/fever blisters--caused by Herpes simplex virus  
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Herpes simplex virus (HSV)   2 types--HSVI/HSVII  
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Hydrophobia   when rabid animal/human tries to swallow, throat muscles ccontract in painful spasm--animals refuse to even look at water and will drool rather than swallow saliva--death due to resp paralysis results after several days of sx  
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Kaposi's sarcoma   Human Herpes virus 8 (HHV8)--tumors appear as purplish-brown areas on skin--most seen in AIDS pts--isolated from saliva/semen--sexual contact primary mode of transmission--seen mostly in homosexual males--other skin ca/one type of lymphoma associated  
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Latency   person infected with herpes virus harbors viruses for life  
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Negri bodies   viral materials can be dx in brain tissue of biting animal by checking for black inclusions--rabies  
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Rabies   rabio--to rave, be mad--virus is bullet shaped, quite common in wild animals--raccoons/skunks--bitten/scratched contaminated with virus-containing saliva--infects all warm-blooded animals--abundant and wild--target organ is CNS-slow groing  
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Recurrence   Herpes viruses likkely may reactivate later in life to cause additional disease--may occur once or many times despite high Ab titers against viruses--usually reduced area of infection  
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Roseola   Human Herpes Virus 6--causes high fever that lasts 3-5 days with rash appearing at end of fever in about 10% of cases  
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Smallpox   lg virion with multilayered surface--complex structure--DNA--only virus eradicated--concern for bioterrorist usage--  
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Warts   naked virions--DNA viruses--cuased by papilloma viruses--spread via direct contact with skin--grows slowly--causes plantar warts, flat warts, and condyloma acuminata--sexually transmitted warts grow on genitalia  
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