Natural Immunity
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| Which line of defense provides specificity and long-term immunity? | acquired immunity provides specificity and long-term immunity
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| List seven natural physical barriers to infection | skin, mucus, cilliated epithelial cells,
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| List 5 specific factors of the body's natural immunity that reduce infection and explain how they reduce infection | mucus--traps airborne microbes, fluid flow--flushes out pathogens, GI tract--acid kills microbes, bodily secretions containing lysozyme--degrades bacterial cell walls, iron-binding proteins--prevent adequate nutrition for bacteria
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| Where is lysozyme found and what does it do? | found in all bodily secretions--degrades bacterial cell walls
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| How does complement kill microbes? | complement proteins circulate through body and bind to bacterial-bound antibodies--to bacterial polysaccharides to form membrane attack complex(C6-C7-C8-C-9) produce pores in bacterial membrane--leakage and lysis of microbe
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| What are the functions of C3 and C5a? | chemotactic factors that recruit phagocytic cells to the site of infection
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| What is the function of polymorphonuclear leukocytes (PMNs), or neutrophils? | engulf and digest foreign matter
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| How abundant are PMNs? | comprise 55% of all white blood cells
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| what do PMNs and macrophages both have receptors for? | IgG antibodies and the C3b component of complement
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| List some things that inhibit phagocytes | Low pH environments, poorly oxygenated tissue, and fluid-filled spaces inhibit phagocytes
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| what host response do basophils and mast cells stimulate? | inflammation
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| what agents do eosinophils help fight? | release toxins that fight organisms that are too large for phagocytes to ingest, such as worms
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Created by:
heatherlvn
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