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Phamacology Neurological Drugs chapter 15

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When groups of neurons (nerve cells in the brain) spontaneously begin to send out electrical impulses in an abnormal, uncontrolled (electrical storm) way it is called   epilepsy.  
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Grand mal seizures are characterized by:   1. LOC (loss of consciousness). 2. Violent rapid contraction and relaxation of the muscles (tonic-clonic seizures). 3. Tongue biting. 4. Incontinence (loss of bowel and/or bladder control).  
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Petit mal seizures are characterized by:   1. Disorientation. 2. Twitching (facial).  
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Petit mal seizures are AKA   absence seizures  
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Absence seizures are more common in   children.  
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Narcolepsy is a type of absence seizure characterized by an   unexpected sudden LOC.  
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A warning sign or symptom of an impending seizure is called an   aura (sensory disturbances).  
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The period of time just after a seizure when the victim is confused is called the   postictal period (5-30 minutes).  
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Medications used to treat seizures are called   antiseizure medications or antiepileptics or anticonvulsants. AAA  
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Antiseizure medications include:   1. Dilantin AKA phenytoin. 2. Luminal AKA phenobarbital (“phenobarb”). 3. Lamictal. 4. Keppra. 5. Topamax.  
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Use of Topamax during pregnancy (gestation) has been linked to birth defects such as   cleft labia and/or palate.  
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Extreme seizure activity is called   status epilepticus.  
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A medication used to treat status epilepticus is   Diastat AKA diazepam.  
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Alzheimer’s disease (AD) is characterized by (extreme dementia)   an irreversible and progressive loss of neurons in the cerebral cortex.  
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Manifestations include progressive difficulty with   memory, judgment, and reasoning AKA dementia.  
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Drugs to treat AD(Alzheimer's disease) include:   1. Aricept. 2. Exelon. 3. Namenda.  
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Parkinson’s disease (PD) is characterized by:   1. Shaking tremors. 2. Muscle rigidity. 3. Bradykinesia (slowness of movement). 4. Mask-like facial expression. 5. Drooling. 6. Shuffling gait progressing to a loss of ability to ambulate.  
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PD (Parkinson's disease) is caused by a deficiency of a neurotransmitter in the brain called   dopamine.  
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Drugs to treat PD (Parkinson's disease) include:   1. Duodopa or Parcopa or Sinemet AKA carbidopa + levodopa. 2. Requip. 3. Mirapex.  
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Mirapex is also used to treat   restless leg syndrome (RLS).  
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Medications used to treat insomnia are called   hypnotics.  
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Hypnotics include:   1. Ambien. 2. Lunesta. 3. Rozerem. 4. Restoril AKA temazepam. 5. Dalmane AKA flurazepam.  
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OTC hypnotics include:   1. Nytol. 2. Sominex.  
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These OTC hypnotics contain   Benadryl AKA diphenhydramine.  
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Benadryl (diphenhydramine) is also classified as an   antihistamine.  
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A common side effect of antihistamines is   drowsiness.  
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