Clearance and transport
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each of the black spaces below before clicking
on it to display the answer.
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| Define clearance | Volume of plasma cleared of a substance per unit time
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| If substance X is filtered and completely reabsorbed, what is the clearance of X? | Zero
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| Criteria for the clearance of a substance to be an indicator of GFR | Freely filtered, not reabsorbed or secreted, not metabolized or produced
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| For inulin, the clearance is equal to the | GFR
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| For PAH, the clearance is equal to the | Renal plasma flow
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| If clearance<GFR, there has been net | Reabsorption
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| If clearance=GFR, there has been | No net reabsorption or secretion
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| If clearance>GFR, there has been net | Secretion
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| Creatinine clearance is mostly _____ of urine flow | Independent
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| As GFR decreases, creatinine clearance | Decreases
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| Normal plasma value of creatinine | 1 mg/dl
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| Renal urea absorption is ____ on urine flow | Dependent
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| In volume depletion, the BUN:Cr ratio | Increases
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