chap 22
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| SSRI | antidepressant | depression,anxiety disorders (panic disorder, obasessive compulsive disorder | block reuptake of serotonin and less effect on reuptake of norepinephrine | nervousness, dizziness,insomnia,male sexual dysfunction (priapism and impotence); fewer autonomic effect and less sedation than Tricyclic | better side effect profile;used in the morning b/c tend to increase alertness;used in caution with seizure,hepatic,diabetes,bipolar
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| MAOI | antidepressant | not a choice of depression treatment, only used when pt fails to respond to other drugs | bind irreversibly to an enzyme monoamine oxidase (MAO) | hypertensive crisis (occipital headache,palpitation,neck stiffness,soreness,nausea and vomitting,sweating,photophobia |
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| lithium | mood-stabilizing drug | mood stabilizer: treat or prevent the manic phase of bipolar disorder | reduce formation of IP3 | drowsiness,weight gain,fine hand tremor,polyuria,hypothyroidism | low therapeutic index' overdose: neurotoxicity,cardiac toxicity,arrhythmia,nausea,vomiting;nonsteroidal anti-inflammatory and diuretics decrease lithium clearance, increase level
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| Atomoxetine | CNS stimulant | ADHD | cardiovascular incidents (high blood pressure, MI,sudden death),decrease in growth and weight gain in children | unique norephinephrine reuptake inhibitor for ADHD
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| Modafinil | CNS stimulant | ADHD in children | not approved for ADHD, "off-label" drug for ADHD
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| Amitriptyline | tricyclic's, tertiary amines | depression | block serotonin reuptake to a greater exten than do secondary amines | more sedation adn autonomic side effects than secondary amines |
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| Nortriptyline | Tricyclic, secondary amines | depression | block norepinephrine reuptake than serotonin reuptake | autonomic side effects and sedation (less than amitriptyline) |
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| Olanzapine | atypical antipschotic agents | positive and negative sypmtoms of schizophrenia | chemical analog of clozapine | sedation,weight gain | produce few EPS effects than haloperidol, fewer autonomic side effects
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| Amphetamines | CNS stimulant | ADHD, sleep apnea, shift-work sleep, obesity | Schedule II, CV incidents, Decreased growth & weight gain |
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| Typical antipsychotics (1st generation) | antipsychotic drugs | Psychoses, Schizophrenia, Tourette’s, Agitation PRN | have equal or greater affinity for D2 receptors than for 5 HT2 receptors, block dopamin and serotonin | Extrapyramidal symptoms(EPS)(akathisia, pseudoparkinsonism,dystonias), Tardive dyskinesia |
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| Atypical antipsychotic drugs (2nd gen) | antipsychotic drugs | have greater affinity for 5-HT receptors than for D2 receptors, block dopamin and serotonin | fewer EPS symptoms than typical
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| All antidepressant medications | Box warning | risk of incresased suicidal thoughts and behavior in children and adolescents and adults |
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| Tricyclic | antidepressant | depression | block neuronal reuptake of norepinephrine and serotonin | autonomic side effects(hypotension,sinus tachycardia,excessive sedation,seizures), cardiac arrhythmia) | used at night b/c of its sedation
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Review the information in the table. When you are ready to quiz yourself you can hide individual columns or the entire table. Then you can click on the empty cells to reveal the answer. Try to recall what will be displayed before clicking the empty cell.
To hide a column, click on the column name.
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You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
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