Drug Classes
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| Carbachol | nonselective cholinergic agonist (carbamate bioisostere, less prone to HOH)
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| Acetylcholine | nonselective cholinergic agonist
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| Methacholine | selective muscarinic agonist (less prone to HOH)
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| Pilocarpine | selective muscarinic agonist (tertiary amine)
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| Bethanechol | selective muscarinic agonist (long acting)
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| Muscarine | selective muscarinic agonist
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| Edrophonium | competitive, reversible AChE inhibitor
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| Donepezil | competitive, reversible AChE inhibitor (tertiary)
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| Pyridostigmine | noncompetitive, reversible AChE inhibitor (slow onset, long duration)
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| Neostigmine | noncompetitive, reversible AChE inhibitor (rapid onset, intermediate duration)
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| Physostigmine | noncompetitive, reversible AChE inhibitor (tertiary)
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| Demercarium | noncompetitive, reversible AChE inhibitor
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| Ambenonium | noncompetitive, reversible AChE inhibitor
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| Echothiophate | irreversible AChE inhibitor
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| Parathion | irreversible AChE inhibitor
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| Malathion | irreversible AChE inhibitor
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| Sarin | irreversible AChE inhibitor
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| Soman | irreversible AChE inhibitor
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| Tabun | irreversible AChE inhibitor
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| Pralidoxime | organophosphate poisoning antidote
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| Homatropine | direct acting anticholinergic (topical admin=local effect)
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| Tropicamide | direct acting anticholinergic (topical admin=local effect)
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| Cyclopentolate | direct acting anticholinergic (topical admin=local effect)
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| Atropine | direct acting anticholinergic
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| Scopolamine | direct acting anticholinergic
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| Ipratropium | direct acting anticholinergic (quaternary)
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| Tiotropium | direct acting anticholinergic (quaternary)
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| Dicyclomine | direct acting anticholinergic
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| Oxybutynin | direct acting anticholinergic
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| Tolterodine | direct acting anticholinergic (selectivity for bladder tissue)
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| Trospium | direct acting anticholinergic (quaternary)
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| Solifenacin | direct acting anticholinergic (selective M3>M1)
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| Darifenacin | direct acting anticholinergic (selective M3>M1)
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| Glycopyrrolate | direct acting anticholinergic (quaternary)
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| Hemicholinium | indirect acting anticholinergic - block active transport of choline into nerve terminal
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| Vesamicol | indirect acting anticholinergic - block transport of ACh into vesicle
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| Botulinum toxin | indirect acting cholinergic - prevent vesicle fusion & release of ACh
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| Nicotine | nicotinic agonist
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| DMPP | nicotinic agonist (selective for autonomic ganglionic cells)
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| Hexamethonium | ganglionic blocker
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| Trimethaphan | ganglionic blocker
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| Mecamylamine | ganglionic blocker
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| Isoproterenol | nonselective beta agonist
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| Dobutamine | beta-1 selective agonist
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| Metaproterenol | short acting beta-2 selective agonist
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| Terbutaline | short acting beta-2 selective agonist
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| Albuterol | short acting beta-2 selective agonist
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| Salmeterol | long acting beta-2 selective agonist
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| Formoterol | long acting beta-2 selective agonist
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| Phenylephrine | alpha-1 selective agonist
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| Tetrahydrozoline | alpha-1 selective agonist
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| Naphazoline | alpha-1 selective agonist
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| Clonidine | alpha-2 selective agonist
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| Amphetamine | indirect adrenergic agonist - releasing agent
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| Methamphetamine | indirect adrenergic agonist - releasing agent
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| Cocaine | indirect adrenergic agonist - reuptake inhibitor
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| Selegiline | indirect adrenergic agonist - MAO inhibitor
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| Ephedrine | mixed action adrenergic agonist. direct alpha & beta, and indirect acting (erythro isomer)
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| Pseudoephedrine | mixed action adrenergic agonist. predominately indirect acting(threo isomer)
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| Phentolamine | nonselective alpha antagonist
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| Phenoxybenzamine | nonselective alpha antagonist
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| Prazosin | selective alpha-1 antagonist
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| Terazosin | selective alpha-1 antagonist (+ apoptosis of prostate cells)
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| Doxazosin | selective alpha-1 antagonist (+ apoptosis of prostate cells)
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| Alfuzosin | selective alpha-1 antagonist
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| Tamsulosin | selective alpha-1a antagonist
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| Silodosin | selective alpha-1a antagonist
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| Yohimbine | selective alpha-2 antagonist
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| Propranolol | nonselective beta antagonist
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| Pindolol | nonselective beta antagonist + ISA
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| Metoprolol | selective beta-1 antagonist
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| Atenolol | selective beta-1 antagonist
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| Labetolol | nonselective beta antagonist + alpha-1 antagonist
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| Carvedilol | nonselective beta antagonist + alpha-1 antagonist + anti-inflammatory
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| Reserpine | indirect andrenergic antagonist - block vesicular monoamine transporter, depleting NE
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| Tyramine | indirect adrenergic antagonist - "false transmitter" that displaces NE
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| Metyrosine | indirect adrenergic antagonist - inhibit tyrosine hydroxylase (TH)
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Created by:
steponmegrace
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