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Drugs recognition: chap 15

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
rosuvastatin (Crestor)   HMG CoA Reductase Inhibitors “Statins”  
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atorvastatin (Lipitor)   HMG CoA Reductase Inhibitors “Statins”  
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simvastatin (Zocor)   HMG CoA Reductase Inhibitors “Statins”  
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pravastatin (Pravachol)   HMG CoA Reductase Inhibitors “Statins”  
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lovastatin (Mevacor)   HMG CoA Reductase Inhibitors “Statins”  
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fluvastatin (Lescol)   HMG CoA Reductase Inhibitors “Statins”  
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pitavastatin (Livalo)   HMG CoA Reductase Inhibitors “Statins”  
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cholestyramine (Questran)   Bile Acid Binding Resins  
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colestipol (Colestid)   Bile Acid Binding Resins  
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colesevelam (Welchol)   Bile Acid Binding Resins  
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ezetimibe (Zetia)   Cholesterol Absorption Inhibitor  
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ezetimibe/simvastatin (Vytorin)   Cholesterol Absorption Inhibitor  
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gemfibrozil (Lopid)   Fibric Acid Derivatives  
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fenofibrate (Tricor, Antara, Lipofen, Trilipix)   Fibric Acid Derivatives  
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niacin (Niaspan-rx, otc’s)   Other Drugs  
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omega-3-fatty acids (ethyl ester) (Lovaza)   Other Drugs  
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Statins indications   Hypercholesterolemia & mixed hyperlipidemia  
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statins adverse effects   GI (constipation, diarrhea, heartburn, abdominal cramps) Liver enzyme elevation & hepatitis Rhabdomyolysis  
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Bile Acid-binding Resins indications   Hypercholesterolemia, pruritis, & diarrhea  
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Bile acid-binding resins adverse effects   constipation, fecal impaction, and rash  
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niacin adverse effects   gastric irrigation, glucose intolerance, myalgia, rhabdomyolysis, myopathies, vasodilation, flusing, prutitus  
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Fibric acid derivatives adverse effects   allergic reactions, blood cell deficiencies, myalgia, rhabdomyolysis and other myopathies  
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rhabdomyolysis is   fatal form of skeletal muscle toxicity (myopathy)  
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etimibide (Zetia) ezetimibide/simvastatin indications   Hypercholesterolemia  
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cholesteron absorption inhibitors: etimibide (Zetia) ezetimibide/simvastatin adverse effects   Headache Myalgia  
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niacin indications   Mixed hyperlipidemia HDL deficiency  
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anticoagulant drugs indications   Patients who have had HIT Unstable angina Acute MI  
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anticoagulant drugs adverse effects   Vasodilation, pruritis (itching), & flushing Hepatitis GI Hyperglycemia  
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omega-3 fatty acids   lower triglyceride levels, improve LDL-c to HDL-C ratio  
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Fibric acid derivatives gemfibrozil (Lopid) fenofibrate (Tricor) indications   Hypertriglyceridemia Mixed hyperlipidemia  
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Fibric acid derivatives gemfibrozil (Lopid) fenofibrate (Tricor) contraindication   avoid with statins  
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Fibric acid derivatives moa   Decrease VLDL & LDL while raising HDL  
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drug to increase HLD   niacin  
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niacin contraindicated with   pt with diabetes  
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Bile Acid-binding Resins moa   Binds with bile acids to prevent recycling which makes the liver produce more from the cholesterol , reduce cholesterol LDL  
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