| Question |
Answer |
| Ankylosing spondylitis |
autoimmune disease, HLA B-27 |
| First group of muscles involved in Duchenne muscular dystrophy? |
pelvic girdle |
| Vitamin K deficiency |
bruising and bleeding |
| Reiter's syndrome |
arthritis, Urthritis, conjunctivitis and skin rash |
| Fissures in articular cartilage and decreased proteoglycan within the matrix |
osteoarthritis |
| deficiency of vitamin B12 results in this anemia |
megaloblastic anemia |
| Chronic rheumatoid arthritis and splenomegaly |
Felty's syndrome |
| Elephantiasis |
obstruction of draining lymphatics |
| Multiple myeloma |
malignant plasma cells, Bence Jones protein, M spike |
| AIDS |
CD4 (T helper cells) |
| Pyogenic osteomyelitis affects which part of the bone |
metaphysis |
| most common cause of pyogenic osteomyelitis |
Staph. aureus |
| Pathological lesions in basal ganglia |
Parkinson, Huntington, Wilson |
| Excess uric acid |
gout |
| monosodium ureate crystals |
gout, tophi |
| Hashimoto's disease |
hypothyroidism, autoimmune |
| Most common malignant bone tumor |
metastatic tumors |
| most common primary malignant bone tumors |
osteosarcoma |
| Most common location for osteosarcoma |
metaphysis of long bones around knee joint |
| Most common benign tumor in the uterus |
leiomyoma |
| Type of necrosis most common in CNS |
liquefactive |
| Kernicterus |
unconjugated hyperbilirubinemia reaching the basal ganglia of infants |
| Accumulation of glucocerebrosides in the cells |
Gaucher's disease |
| Both UMNL and LMNL occur in |
amyotrophic lateral sclerosis |
| Thiamin deficiency causes |
dry and wet beriberi |
| Hemophilia A |
deficiency of antihemophilic globulin (factor 8) |
| Hemophilia B |
deficiency of Christmas factor (factor 9) |
| Movement of leukocytes in response to concentration gradient of chemokines |
chemotaxis |
| Smoking is a major cause of |
cancer lung, thromboangitis obliterans, chronic bronchitis |
| Implicated in cancer cervix, vagina, and vulva |
Human papilloma virus (types 16 & 18) |
| Signs in Kwashiorkor |
edema, flaky-paint skin, retardation of growth, hepatomegaly |
| Marasmus is caused by |
deficiency of calories (CHO and lipids) |
| T lymphocyte that helps in function of B lymphocyte |
CD4 |
| Most important leukocyte in acute inflammation |
neutrophils |
| Example of granulomatous inflammation |
TB, leprosy, syphilis, Sarcoidosis |
| Lesions in tertiary stage of syphilis |
gumma, cardiovascular syphilis (aneurysm, aortic regurge) and neurosyphilis (meningovascular syphilis, paresis, tabes dorsalis) |
| Important factor in the deline of cervical cancer? |
routine PAP smears |
| Decreased blood proteins |
edema (decreased colloidal OP) |
| Arachnodactayly, subluxation of the lens, cardiac defects and hyperextensibility of the joints, aortic aneurysm |
Marfan's syndrome |
| Albers Shoenberg disease |
marble bone disease, defective function of osteoclast |
| Clinical features of Parkinson disease is related to |
extrapyramidal system (deficiency of dopamine secreted by pigmented neurons in substania nigra of midbrain) |
| Familial hypercholesterolemia is considered as |
most common autosomal dominant disease in USA (cholesterol receptors on liver cells) |
| A 25 year old female represents by weakness o extraocular muscles |
myasthenia gravis |
| Most common symptom in esophageal cancer |
dysphagia |