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A&P.mart.cardio

QuestionAnswer
blood purpose transportation of gases, nutrients, hormones & metabolic waste; regulation of pH & Ions; restriction of fluid losses at injury sites; defense against toxins & pathogens; stabilization of temperature
plasma unique connective tissue; plasma proteins are in solution -don't form like cartilage
hemocytoblasts or pluripotent stem cells
hemocytoblasts divide to produce myeloid stem cells and lymphoid stem cells (which are capable of division)
myeloid stem cells and lymphoid cells divide daughter cells are specialized
whole blood can be fractionated; or separated,
characteristics of whole blood (physical) temperature roughly 38 degrees Centigrade or 100.4 F; viscosity - blood is 5 times more viscous (stickier, more cohesive, & resistant to flow) and has pH of 7.35-7.45 (slightly alkaline)
vein used to collect blood median cubital vein
venipuncture 1. veins easy to locate 2. walls of veins thinner than artereis & 3. blood pressure in venous system lower than arterial blood-most common clinical procedures examine venous blood
arterial puncture "arterial stick" used to check efficiency of gas exchange at the lungs - drawn from radial artery at wrist of brachial artery at elbow
plasma and interstitial fluid constitute 92 percent of the extracellular fluid (ECF) in the body
3 primary classes of plasma proteins 1. albumins; 2. globulins & 3) fibrinogen - make up 99% of plasma proteins
albumins 60% of plasma protein, osmotic pressure & transport fatty acids, etc.
glbulins 35% of proteins antibodies or immunoglobins; transport globulins (carry iron) transferrin
fibrinogen clotting - 4% of plasma proteins
red blood cells 1 microliter (or 1 cubic millimeter (mm#) contain 4.5-6.3 million RBc's (for men) - RBC's are so numerous they account for
hematocrit percentage of whole blood occupied by cellular elements
normal hematocrit MALES have more RBC's than females
hematocrit is expressed in commonly reported at volume of packed red blood cells (VPRC) or simply the packed cell volume (PCV)
dehydrationg means the hematocrit will increase (due to less water; reduction in plasma volume)
Why are RBC's concave? 1. greater surface area 2. form stacks, like dinner plates, in narrow blood vessels 3. can bend and flex
RBC's have few organelles (in humans & mammals) energy demands are low, mitochondria don't "steal it" therefore RBC's can't reapir
hemoglobin conservation & recycling phagocytes engulf aging RBCS or they hemolyze (rupture)
hemoglobin Hb recylced globular proteins disassembled into component amino acids (re-used in bone marrow red cell production); heme units stripped of iron & converted to biliverdin and then bilirubin (transferred to liver & excreted as bile)
what happens to iron in blood? large quantities of free iron are toxic; so iron is bound to transferrin, a plasma protein; taken to form new red blood cells
hypoxia hypo - below - ox (presence of oxygen)
hemolytic disease of the newborn (HDN) Rh factor - mother's blood can cross placenta and attack Rh-positive fetus - fatalities prevented by RhoGam (which destroys fetal anti-Rh antibodies before they get into mother's bloodstream; therefore the immune system is not immobolized
Created by: walterina4327
 

 



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