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Endocrine 1,2,3

GenericBrandPharmacologic CategoryIndicationSide Effects
Metformin (PO) Glucophage, Glucophage XR Biguanide Type 2 DM, PCOS diarrhea, nausea, vomiting US Boxed Warning: lactic acidosis
Sitagliptin (PO) Januvia Dipeptidyl peptidase (DPP-4) inhibitor Type 2 DM headache, nasopharyngitis
Empagliflozin (PO) Jardiance Na-glucose cotransporter inhibitor 2 (SGLT2 inhibitor) Type 2 DM, HF UTI
Glimepiride (PO) Amary Sulfonylurea Type 2 DM hypoglycemia, weight gain
Glipizide (PO) Glucotrol, Glucotrol XL Sulfonylurea Type 2 DM hypoglycemia, weight gain
Glyburide (PO) Glynase Sulfonylurea Type 2 DM hypoglycemia, weight gain
Pioglitazone (PO) Actos Thiazolidinedione (TZD) Type 2 DM edema, weight gain, upper respiratory tract infection Boxed Warning: may exacerbate congestive HF & CI in NYHA Class III and IV
Liraglutide (SQ) Victoza, Saxenda Glucagon-like peptide-1 (GLP-1) receptor agonist Type 2 DM, chronic weight management nausea, vomiting, diarrhea, constipation Boxed Warning: may increase risk of thyroid c-cell tumoR
Insulin detemir (SQ) Levemir Insulin, long acting Type 1 DM, type 2 DM hypoglycemia, weight gain
Insulin glargine (SQ) Lantus, Toujeo, Basaglar Insulin, long acting Type 1 DM, type 2 DM hypoglycemia, weight gain
Insulin NPH (SQ) Humulin N, Novolin N Insulin, intermediate acting Type 1 DM, type 2 DM hypoglycemia, weight gain
Insulin aspart (SQ) Novolog Insulin, rapid acting Type 1 DM, type 2 DM hypoglycemia, weight gain
Insulin lispro (SQ) Humalog Insulin, rapid acting Type 1 DM, type 2 DM hypoglycemia, weight gain
Insulin regular (SQ, IV) Humulin R, Novolin R Insulin, short-acting Type 1 DM, type 2 DM, DKA hypoglycemia, weight gain
Levothyroxine (PO, IV) Synthroid, Levoxyl Thyroid product Hypothyroidism weight loss, palpitations, diarrhea, insomnia, heat intolerance Boxed Warning: not intended for weight loss Notes: narrow therapeutic index drug (monitoring recommended); not all generic products are therapeutically equivalent
Thyroid, dessicated (PO) Armour Thyroid Thyroid product Hypothyroidism weight loss, palpitations, diarrhea, insomnia, heat intolerance Boxed Warning: not intended for weight loss Notes: narrow therapeutic index drug (monitoring recommended); not all generic products are therapeutically equivalent
Sitagliptin & Metformin (PO) Janumet, Janumet XR
Drospirenone & ethinyl estradiol (PO) Yasmin, Yaz Contraceptive Contraception, acne nausea, change in menstrual flow, breast tenderness, thromboembolic disorders, HA| Boxed Warning: increased risk of CV events in women >35 yo who smoke Notes: CI in hepatic dysfunction, thromboembolic disorders, breast cancer & CV disease
Levonorgestrel & ethinyl estradiol (PO) Lutera, Levora, Seasonique Contraceptive Contraception, acne nausea, change in menstrual flow, breast tenderness, thromboembolic disorders, HA| Boxed Warning: increased risk of CV events in women >35 yo who smoke Notes: CI in hepatic dysfunction, thromboembolic disorders, breast cancer & CV disease
Norethindrone & ethinyl estradiol (PO) Junel, Loestrin, Microgestin Contraceptive Contraception, acne nausea, change in menstrual flow, breast tenderness, thromboembolic disorders, HA| Boxed Warning: increased risk of CV events in women >35 yo who smoke Notes: CI in hepatic dysfunction, thromboembolic disorders, breast cancer & CV disease
Norethindrone, ethinyl estradiol & ferrous fumarate (PO) Lo Loestrin Fe, Microgestin Fe Contraceptive Contraception, acne nausea, change in menstrual flow, breast tenderness, thromboembolic disorders, HA| Boxed Warning: increased risk of CV events in women >35 yo who smoke Notes: CI in hepatic dysfunction, thromboembolic disorders, breast cancer & CV disease
Norgestimate & ethinyl estradiol (PO) Ortho Tri-Cyclen Lo, Tri-Sprintec, Sprintec Contraceptive Contraception, acne nausea, change in menstrual flow, breast tenderness, thromboembolic disorders, HA| Boxed Warning: increased risk of CV events in women >35 yo who smoke Notes: CI in hepatic dysfunction, thromboembolic disorders, breast cancer & CV disease
Norgestrel & ethinyl estradiol (PO) Crysell-28, Low-Ogestrel Contraceptive Contraception, acne nausea, change in menstrual flow, breast tenderness, thromboembolic disorders, HA| Boxed Warning: increased risk of CV events in women >35 yo who smoke Notes: CI in hepatic dysfunction, thromboembolic disorders, breast cancer & CV disease
Estrogens, conjugated (equine) (PO, topical) Premarin Estrogen derivative Vasomotor symptoms & vaginal atrophy associated w/ menopause application site irritation (patch) abdominal pain, breast tenderness, CI - thromboembolic disorders (MI, stroke, VTE) Box Warning: increased risk of breast & endometrial cancer (if not used w/ progestin in women w/ uterus) should not be used for CV di
Estradiol (transdermal, PO) Transdermal: Vivelle Dot, PO: Estrace Estrogen derivative Vasomotor symptoms & vaginal atrophy associated w/ menopause
Medroxyprogesterone (PO) Provera Progestin Abnormal uterine bleeding, secondary amenorrhea acne, HA, amenorrhea abnormal menstrual bleeding, Box Warning: increased risk of breast cancer; DNU for dementia or CV disease prevention | CI in thromboembolic disorders, CV disease, estrogen/ progesterone dependent tumors, undiagnosed abnormal genital b
Testosterone gel (topical) AndroGel, Fortesta, Vogelxo Androgen Hypogonadism contact dermatitis, acne, increased PSA, emotional lability, HTN BW:secondary exposure may result in virilization (especially in children); CI in males w/ breast or prostate cancer & pregnant women
Alendronate (PO) Fosamax Bisphosphonate Osteoporosis dyspepsia, GERD hypocalcemia, atypical fractures, osteonecrosis of jaw CI in pts w/ esophagus abnormalities admin ≥30 min before food/drink (except plain water); remain upright 30 min following dose to reduce esophageal irritation
Ibandronate (PO, IV) Boniva Bisphosphonate Osteoporosis dyspepsia, GERD hypocalcemia, atypical fractures, osteonecrosis of the jaw PO: CI in pts w/ esophagus abnormalities; admin ≥60 min before food/drink (except plain water); remain upright for 60 min after dose to reduce esophageal irritation
Raloxifene (PO) Evista Selective estrogen receptor modulator (SERM) Osteoporosis, breast cancer prevention hot flashes, leg cramps, peripheral edema, arthralgia BW: increased risk of thromboembolism,death caused by stroke in pts with CV disease
Sildenafil (PO) Viagra, Revatio Phosphodiesterase-5 enzyme (PDE5) inhibitor ED, PAH (pulmonary arterial HTN) priapism, HA, flushing, visual disturbance CI w/ concomitant use of nitrates (may cause severe hypotension)
Tadalafil (PO) Cialis Phosphodiesterase-5 enzyme (PDE5) inhibitor ED, BPH priapism, HA, flushing, visual disturbance CI w/ concomitant use of nitrates (may cause severe hypotension)
Created by: Aware19
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