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MODULE 19: KEY TERMS

Sterile product compounding

QuestionAnswer
Anteroom: Area in close proximity to the cleanroom where pharmacy technicians perform support tasks.
Aseptic technique: A series of steps and precautions that are used to decrease the chance of contamination during preparation of a sterile product.
Barrier isolater: Prevent cross-contamination of airborne materials.
Beyond-use date: The date assigned by the pharmacy to a compounded or repackaged medication beyond which the medication should not be used.
Buffer area: Area in which hoods are kept and IV preparation takes place.
Direct compounding area: Critical area within the ISO class 5 where critical sites are exposed to unidirectional HEPA-filtered air.
Horizontal laminar-flow hood: A laminar-flow hood with the HEPA filter perpendicular to the work surface. The clean air blows from the filter toward the person working in the hood, thereby keeping particulate matter away from the work surface.
Large-volume parenterals: A parenteral medication that is used when the fluid itself is the treatment.
Primary engineering control: Device o room that provides an ISO class 5 environment for compounding.
Segregated compounding area: A designated space that is restricted to preparing low-risk compounded sterile products with beyond-use dates of 12 hours or less.
Small-volume parenterals: Parenteral medication that contains just enough fluid volume to safely deliver the medication into a patient's vein.
Subcutaneous: Describing the layer below the cutaneous (dermal) skin layer. This layer is a common location for injections.
Total parenteral nutrition: A large-volume IV bag given to patients who cannot consume food (NPO) or a nutritional formula (like Ensure) for a prolonged period of time. TPN solutions contain major nutrients (carbohydrates, proteins, fats) along with electrolytes and vitamins.
Vertical laminar-flow hood: A laminar-flow hood with the HEPA filter parallel to the work surface. Clean air blows straight down toward the work surface.
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