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MODULE 13: KEY TERMS
Basic pharmacology
Question | Answer |
---|---|
Accommodation: | The automatic adjustment of the lens in the eye to improve the clarity during distance changes. |
Agonist: | Stimulating or increasing the effect of a process; an inducer. |
Alpha agonists: | Topical medications that increase the excretion of water from the eye to reduce IOP. |
Antagonist: | Inhibiting or decreasing the effect of a process' an inhibitor. |
Beta blockers: | Topical medications that inhibit the ciliary epithelium, which is responsible for excreting water near the iris and optic nerve , to reduce IOP. |
Bioavailability: | Measure of how much a medication actually gets into the blood to be distributed into the body. |
Bradycardia: | Slow heart rate (usually 60 beats per minute). |
Cytochrome P450 enzymes: | A large group of enzymes responsible responsible for the metabolism o many medications. |
Distribution: | Process by which the body moves medication from the bloodstream to tissues or organs to exert its effect. |
Diuretics | Medications that decrease the amount of water secreted into the eye by inhibiting carbonic anhydrase in the eye. |
Drug-disease interactions: | When medications are harmful due to a medical condition. |
Drug-food interactions: | When medications are affected by a patient's consumption of certain foods or drinks. |
Drug-to-drug interactions: | When two medications are mixed together to create an effect. |
Excretion: | The process of expelling waste from the body by urination or defecation. |
Glaucoma: | A condition in which too much water around the retina and optic nerve increases the IOP. |
Metabolize: | The breaking down of medications into a from that can be used by the body. |
Mydriasis: | A condition in which constrictor muscles of the eye relax, so the pupils dilate far vision; farsightedness. |
Pharmacodynamics: | The study of what medications do to the body. |
Pharmacokinetics: | The study of what the body does to medications. |
Pharmacology: | The study of medications (including their: composition, indications, side effects, and how they act in the body). |
Prostaglandin Analogs: | Topical medications that increase the excretion of water from the eye to reduce IOP. |
Protein Displacement: | Medications that are bound to plasma proteins are inactive , but they become active if they are displaced. |
QT Prolongation: | When the heart muscle takes longer to recharge between beats, prolonging the QT interval (time of ventricular activity). |
Rebound Hypertension: | Rise in blood pressure after withdrawal or lowering of a drug dose (typically a high blood pressure medicine). |
Rhabdomyolysis: | Death of muscle tissue, releasing muscle fiber contents into the blood. |
Solubility: | Characteristics that determine whether a medication will be administered orally or by injection. |
Synergism: | When two medications work together better than if either medication is given separately. |
Tachyphylaxis: | The tolerance or wearing-off effect of certain medications. |
Therapeutic index: | Measure of how safe medications are; the higher the therapeutic index, the safer a medication is. |
Therapeutic window: | The optimal range in which medications are most effective. |