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CV 4
Generic | Brand | Pharm Category | Indications | Essential Knowledge |
---|---|---|---|---|
Amiodarone (PO, IV) | Pacerone, Nexterone | Antiarrhythmic | AF (rhythm control), ventricular fibrillation, ventricular tachycardia | Key Side Effects: hypothyroidism, hyperthyroidism, pulmonary toxicity, hepatotoxicity US Boxed Warnings: life-threatening arrhythmias, pulmonary toxicity, hepatotoxicity Notes: many DDIs |
Digoxin (PO, IV) | Digitek, Digox, Lanoxin | Cardiac glycoside | AF (rate control), HF | Key Side Effects: nausea, vomiting, visual changes Notes: narrow therapeutic index (toxicity may occur at conc close to therapeutic range, monitoring recommended); signs of toxicity include nausea, vomiting and visual changes; many DDIs |
Ezetimibe (PO) | Zetia | Cholesterol absorption inhibitor | Dyslipidemia | Key Side Effects: diarrhea |
Fenofibrate (PO) | Tricor, Trilipix | Fibric acid derivative | Dyslipidemia | Key Side Effects: dyspepsia, myopathy/ rhabdomyolysis, elevated hepatic transaminases |
Gemfibrozil (PO) | Lopid | Fibric acid derivative | Dyslipidemia | Key Side Effects: dyspepsia, myopathy/ rhabdomyolysis, elevated hepatic transaminases |
Atorvastatin (PO) | Lipitor | HMG-CoA reductase inhibitor | Dyslipidemia, CAD, stroke | Key Side Effects: myopathy/ rhabdomyolysis Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding |
Lovastatin (PO) | Mevacor | HMG-CoA reductase inhibitor | Dyslipidemia, CAD, stroke | Key Side Effects: myopathy/ rhabdomyolysis Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding |
Pravastatin (PO) | Pravachol | HMG-CoA reductase inhibitor | Dyslipidemia, CAD, stroke | Key Side Effects: myopathy/ rhabdomyolysis Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding |
Rosuvastatin (PO) | Crestor | HMG-CoA reductase inhibitor | Dyslipidemia, CAD, stroke | Key Side Effects: myopathy/ rhabdomyolysis Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding |
Simvastatin (PO) | Zocor | HMG-CoA reductase inhibitor | Dyslipidemia, CAD, stroke | Key Side Effects: myopathy/ rhabdomyolysis Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding |
Omega-3 fatty acids (PO) * | Lovaza, Vascepa | Omega-3 fatty acids | Dyslipidemia | Key Side Effects: diarrhea, nausea, dysgeusia, eructation |
Niacin (ER), (PO)* | Niaspan | Water-soluble vitamin | Dyslipidemia | Key Side Effects: flushing, pruritus |