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Cardio3
Cardio3 Essential Knowledge
Generic/Brand | Side effects |
---|---|
Dabigatran/ Pradaxa (PO) | Key Side Effects: bleeding, dyspepsia US Boxed Warnings: premature discontinuation increases risk of thrombotic events Other Notes: swallow whole; dispense and store in original packaging; discard 4 months after opening |
Apixaban/ Eliquis (PO) | Key Side Effects: bleeding US Boxed Warnings: premature discontinuation increases risk of thrombotic events |
Rivaroxaban/ Xarelto (PO) | Key Side Effects: bleeding US Boxed Warnings: premature discontinuation increases risk of thrombotic events |
Warfarin/ Coumadin, Jantoven (PO) | Key Side Effects: bleeding US Boxed Warnings: bleeding risk Other Notes: narrow therapeutic index drug (toxicity may occur at concentrations close to therapeutic range; therapeutic monitoring recommended with INR) Other Notes: dose dependent tablet colors; uniform vitamin K intake recommended; many drug interactions |
Enoxaparin/ Lovenox (PO) | Key Side Effects: bleeding, hyperkalemia, HIT: Heparin-induced thrombocytopenia. US Boxed Warnings: increased risk of epidural or spinal hematoma in patient undergoing spinal puncture. Other Notes: do not expel air bubble from syringe prior to injection |
Heparin/ ---- (IV, SQ) | Key Side Effects: bleeding, hyperkalemia, HIT |
Clopidogrel/ Plavix (PO) | Key Side Effects: bleeding US Boxed Warnings: diminished effectiveness in poor metabolizers |
Dipyridamole & Aspirin/ Aggrenox (PO) | Key Side Effects: bleeding, headache |
Prasugrel/ Effient (PO) | Key Side Effects: bleeding US Boxed Warnings: bleeding risk Other Notes: CI in patients with history of stroke |
Alteplase/ Cathflo, Activase (intracatheter, IV) | Key Side Effects: bleeding Other Notes: CI in patients with severe uncontrolled HTN |