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Neuro/Psych 4
Generic | Brand | Pharmacologic Categories | Common Indications | Essential Knowledge |
---|---|---|---|---|
carbamazepine (PO) | Tegretol | Anticonvulsant | Seizure disorders, bipolar disorder | Key Side Effects: dizziness, drowsiness, headache, ataxia, nausea, vomiting, hyponatremia US Boxed Warnings: risk of serious dermatologic reactions (including SJS and TEN) in patients with certain genetic predisposition; may cause aplastic anemia and agranulocytosis |
lamotrigine (PO) | Lamictal | Anticonvulsant | Seizure disorders, bipolar disorder | Key Side Effects: nausea, vomiting, somnolence, skin rash US Boxed Warnings: risk of serious dermatologic reactions, including SJS |
divalproex (valproic acid derivative) (PO) | Depakote, Depakote ER, Depakene | Anticonvulsant | Seizure disorders, bipolar disorder, migraine prophylaxis | Key Side Effects: drowsiness, weight gain, tremor, hair loss, thrombocytopenia US Boxed Warnings: may cause fatal hepatic failure; may cause life-threatening pancreatitis; fetal toxicity |
topiramate (PO) | Topamax | Anticonvulsant | Seizure disorders, migraine prophylaxis | Key Side Effects: somnolence, dizziness, diplopia, ataxia, memory impairment, weight loss |
levetiracetam (PO, IV) | Keppra | Anticonvulsant | Seizure disorders | Key Side Effects: somnolence, dizziness, diplopia, nausea, vomiting, ataxia, weakness |
oxcarbazepine (PO) | Trileptal | Anticonvulsant | Seizure disorders | Key Side Effects: somnolence, dizziness, diplopia, nausea, vomiting, ataxia, weakness, hyponatremia |
phenobarbital (PO, IM, IV) | - - - - | Anticonvulsant | Seizure disorders | Key Side Effects: somnolence, dizziness, risk of SJS |
phenytoin (PO, IV) | Dilantin | Anticonvulsant | Seizure disorders | Key Side Effects: somnolence, dizziness, gingival hyperplasia, hirsutism, risk of SJS US Boxed Warning: cardiovascular risk with rapid infusion Other Notes: narrow therapeutic index drug (toxicity may occur at concentrations close to therapeutic range; therapeutic drug monitoring is recommended) |
gabapentin (PO) | Neurontin | Anticonvulsant | Seizure disorders, neuropathic pain | Key Side Effects: somnolence, dizziness, ataxia, fatigue, diplopia, xerostomia, blurry vision |
pregabalin (PO) | Lyrica | Anticonvulsant | Seizure disorders, neuropathic pain | Key Side Effects: somnolence, dizziness, ataxia, fatigue, diplopia, xerostomia, blurry vision |