click below
click below
Normal Size Small Size show me how
Infectious Disease 2
Generic | Brand | Pharmacologic Category | Common Indications | Essential Knowledge |
---|---|---|---|---|
meropenem (IV) | Merrem | Carbapenem | Meningitis, HAP, DFI, IAI Activity against: Pseudomonas aeruginosa, ESBL-producing Enterobacteriaceae | Key side effects: diarrhea, hypersensitivity reactions, seizures with excessive doses |
ertapenem (IV) | Invanz | Carbapenem | DFI, IAI Activity against: ESBL producing Enterobacteriaceae | Key side effects: diarrhea, hypersensitivity reactions, seizures with excessive doses |
ciprofloxacin (PO, IV) | Cipro | Fluoroquinolone antibiotic | Pyelonephritis, HAP Activity against: Pseudomonas aeruginosa, atypicals | KSE: QTc prolongation, tendon rupture, Incr Hep Trans, photosensitivity USBW: may cause serious adverse reactions including tendonitis and tendon rupture, peripheral neuropathy, and CNS effects; may exacerbate muscle weakness in pt w/ myasthenia gravis ON: take oral “FQ” 2 hrs b4 or 6 hrs after products containing di or trivalent cations (i.e. dairy, Ca 2+ -fortified juices, oral MV, mineral supp.); increased risk of aortic dissection or rupture, dysglycemias, CNS SE (i.e. disorientation and delirium) |
levofloxacin (PO, IV) | Levaquin | Fluoroquinolone antibiotic | CAP, pyelonephritis Activity against: Pseudomonas aeruginosa, Streptococcus pneumoniae, atypicals | KSE: QTc prolongation, tendon rupture, Incr Hep Trans, photosensitivity USBW: may cause serious adverse reactions including tendonitis and tendon rupture, peripheral neuropathy, and CNS effects; may exacerbate muscle weakness in pt w/ myasthenia gravis ON: take oral “FQ” 2 hrs b4 or 6 hrs after products containing di or trivalent cations (i.e. dairy, Ca 2+ -fortified juices, oral MV, mineral supp.); increased risk of aortic dissection or rupture, dysglycemias, CNS SE (i.e. disorientation and delirium) |
moxifloxacin (ophthalmic, PO, IV) | Ophthalmic: Vigamox, PO, IV: Avelox | Fluoroquinolone antibiotic | Ophthalmic: bacterial conjunctivitis, PO, IV: CAP Activity against: Streptococcus pneumoniae, atypicals | KSE: QTc prolongation, tendon rupture, Incr Hep Trans, photosensitivity USBW: may cause serious adverse reactions including tendonitis and tendon rupture, peripheral neuropathy, and CNS effects; may exacerbate muscle weakness in pt w/ myasthenia gravis ON: take oral “FQ” 2 hrs b4 or 6 hrs after products containing di or trivalent cations (i.e. dairy, Ca 2+ -fortified juices, oral MV, mineral supp.); increased risk of aortic dissection or rupture, dysglycemias, CNS SE (i.e. disorientation and delirium) |
azithromycin (PO, IV) | Zithromax, Z-Pak, Zmax | Macrolide antibiotic | CAP Activity against: Helicobacter pylori, Chlamydia trachomatis, atypicals | Key side effects: diarrhea, QTc prolongation |
clarithromycin (PO, IV) | Biaxin, Biaxin XL | Macrolide antibiotic | CAP Activity against: Helicobacter pylori, Chlamydia trachomatis, atypicals | Key side effects: diarrhea, metallic taste, QTc prolongation |
fidaxomicin (PO) | Dificid | Macrolide antibiotic | CDI Activity against: Clostridioides difficile | Key side effects: nausea Other notes: do not use for systemic infections (no systemic absorption) |
doxycycline (PO, IV) | Vibramycin | Tetracycline antibiotic | SSTI, CAP, tickborne diseases Activity against: MRSA, atypicals | Key side effects: esophagitis (doxycycline only), photosensitivity Other notes: may cause permanent gray-brown discoloration of teeth and/or enamel hypoplasia when given to children; take oral tetracyclines 2 hours before or 6 hours after products containing divalent or trivalent cations (i.e. dairy products, calcium-fortified juices, oral multivitamins, mineral supplements) |
minocycline (PO, IV) | Minocin | Tetracycline antibiotic | SSTI, acne Activity against: MRSA | Key side effects: esophagitis (doxycycline only), photosensitivity Other notes: may cause permanent gray-brown discoloration of teeth and/or enamel hypoplasia when given to children; take oral tetracyclines 2 hours before or 6 hours after products containing divalent or trivalent cations (i.e. dairy products, calcium-fortified juices, oral multivitamins, mineral supplements) |