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CNS Stimulants
Amphetamines, Analeptics & Anorexiants
Term | Definition |
---|---|
Central Nervous System | Brain & spinal cord →the way the body processes all of the incoming information - brain controls most of the functions (including awareness, senses, movement, speech) |
Peripheral Nervous System | - Nerves that branch out from brain and spinal cord who serve as a communication network between CNS and PNS - Divided into Somatic (skin and muscles/conscious activities) and automatics system (unconscious response such as stomach) |
CNS Stimulant: Amphetamines | - Stimulate the release of norepinephrine in the sympathetic nerve pathway - They are often use to ADHD - Model Drug - Methylphenidate or Ritalin - Drugs in this class usually end in the suffix “ate” or “mine” |
CNS Stimulant: Analeptics | - Thought to bind dopamine and keep it from being absorbed - Used to treat Narcolepsy - Model Drug - Modafinil/Provigil - Drugs in this class often end in suffix “nil” |
CNS Stimulant: Anorexiants | - Similar to amphetamines, suppress appetite through hypothalamus, cause euphoria - Used to treat obesity - Model Drug - Phentermine/Adipex-P |
ADRs | Anxious, hyperactive, tachycardia |
Contraindications / Interactions | - Interacts with anesthetics, oral contraceptives, and bronchodilator - Contraindicated with convulsive disorders, COPD, cardiac arrhythmias, hypertension, do not give with antidepressants or within 14 days, glaucoma, pregnancy category X |
Should a COPD patient use CNS Stimulants? | NO (causes respiratory depression) |
What should you always check for CNS Stimulant patients? | Respiration Rate, Heart Rate, and Rhythm |
Is caffeine good to combine with CNS Stimulants | No |
Who are anorexiants intended for? | BMI over 30 (27 if a comorbidity occurs) |