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Hypertension Drugs

Pharma therapy for HTN

QuestionAnswer
HCTZ Thiazide Diuretic
Chlorthalidone Thiazide Diuretic
Metolazone Thiazide Diuretic
Indapamide Thiazide Diuretic
Furosemide Loop Diuretic
Bumetanide Loop Diuretic
Ethacrynic Acid Loop Diuretic
Torsemide Loop Diuretic
Spironolactone (Aldactone) Potassium-Sparing Diuretic
Triamterine (Demadex) Potassium-Sparing Diuretic
Atenolol Beta adrenergic blockers
Pindolol Beta adrenergic blockers
Metoprolol (Lopressor, Toprol XL) Beta adrenergic blockers
Nadol (Corgard) Beta adrenergic blockers
Sotalol Beta adrenergic blockers
Propranolol Beta adrenergic blockers
Dihydropyridine Calcium Antagonists: Channel Blockers Amlodipine (Norvasc) Felodipine
Creatinine levels in renal dysfunction SCr >2.5 or CrCl < 30
Non-dihydropyridine Calcium Antagonists: Channel Blockers Verapamil, Diltiazem (Cardizem)
Contraindications Non-dihydropyridine CCB A,F c/i hepatic dysfunction & hypotension
Non-dihydropyridine CCB Indications for Use Hypertension & Angina. Works via arteriolar/ coronary vasodilation
Non-dihydropyridine CCB Adverse Effects Headache, Peripheral Edema, Weakness, Dizziness
Dihydropyridine CCB MOA V, D Inotropic & Chronotropic effects on the heart
Dihydropyridine CCB Indications for Use V, D HTN, Angina, atrial fibrilation/ flutter, paroxysmal SVT
Dihydropyridine CCB Common SE V, D Headache, Dizziness, Constipation, Bradycardia
Non-Dihydropyridine c/i / cautions V, D Sick Sinus Syndrome, More than first degree AV block, hypotension <90 systolic, acute MI & pulmonary congestion on cray, renal/ hepatic dysfunction
Verapamil (Calan SR) Non-Dihydropiridine CCB
Diltiazem (Cardizem) Non-Dihydropiridine CCB
Classes of Renin Angiotensin System Antagonists ACE-Is & Angiotensin II Receptor Antagonists ARB
Captopril ACE-I
Enalapril ACE-I
Fosinopril. ACE-I.
Ramipril ACE-I
Lisinopril ACE-I
Valsartan Angiotensin II Receptor Antagonist
Candesartan Angio II Rcptr Antag ARB
Irbesartan ARB
Losartan ARB
Prazosin alpha adrenergic blocker
Doxazosin Alpha adrenergic blocker
Terazosin Alpha Adrenergic blocker
Alpha Adrenergic Blocker indications for use HTN & BPH
Contraindications/ Cautions w/ alpha adrenergic Blockers "First Dose Phenomenon", Priapism
Adverse Effects Alpha Adrenergic Blockers Hypotension, somnolence, headache, dizziness
MOA of alpha adrenergic Blockers Block alpha 1 receptors reducing systemic vascular resistance
Name 4 Alpha Blockers & their indication (Pray, Tam, Tera, Dox) Prazosin, Tamsulosin, Terazosin, Doxazosin
Labetalol alpha/beta Adrenergic Blockers
Carvedilol alpha/beta Adrenergic Blockers
alpha/beta Adrenergic Blockers Contraindications, Cautions Hint: 4 listed Asthma, overt cardiac failure, >1st degree heart block, severe Bradycardia, cardiogenic shock, abrupt withdrawl, hepatic dysfunction
alpha/beta Adrenergic Blockers Indications for Use HTN & CHF
alpha/beta Adrenergic Blockers common SE Hypotension, dizziness, fatigue
Name the alpha/beta Adrenergic Blockers Labetolol, Carvedilol
Hydralazine Vasodilator
Minoxidil (Loniten) Vasodilator
Vasodilator c/i, cautions CAD, Mitral Valve Rheumatic heart dz, pheochromocytoma (Minoxidil), caution in pts w/ remake dysfunction & tartrazine sensitivity
Name the Vasodilators Minoxidil (Loniten), Hydralazine
Vasodilator common SE Blood dyscrasias, rash, palpitations, tachycardia, peripheral neuritis, fluid & electrolyte imbalance, pericardial effusion (Minoxidil), caution w/ pts who have remake dysfunction & tartrazine sensitivity
Created by: VOlds@atsu.edu
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