Question | Answer |
(1) ACE-I given as an active drug with active metabolite | captopril |
(2) ACE-I given as ester prodrug converted to active metabolite | enalapril and ramipril |
(1) ACE-I given as active drug, excreted unchanged | lisinopril |
Class causing angioedema, agranulocytosis, neutropenia | ACE inhibitors |
2 classes used in diabetic neuropathy | ACE-I and AT2 R antagonist |
Class that can cause rhabdo-, angioedema and rare thrombocytopenia | AT-II R blockers |
Used in Acutely decompensated heart failure | nesiritide |
BNP analogue | nesiritide |
Nesiritide with an ACE inhibitor can cause | severe hypotension |
Used in SIADH, ADPCKD, and Euvolemic hyponatremia, can cause afib | conivaptan |
MOA of acetazolamide | CA 2 and 4 inhibitor |
Can be used in glaucoma | acetazolamide |
Used as 1st line for edema states | loop diuretics |
Most potent loop diuretic | bumetanide |
Used to treat hyper-calcemic and kalemic states | loop diuretics |
Diuretics help treat hypercalcinuria | Thiazides |
Diuretics useful with renal cysts? | -vaptans |
Diuretics that help treat calcium wasting in osteoporosis? | Thiazides |
Loop diuretic that can be used in Pt’s with sulfa allergy | ethycrinic acid |
2 Diuretic used for primary aldosteronism? | spironolactone and eplerone |
Diuretic that may uncover diabetes in a Pt? | HCTZ |
Diuretic that may induce hypernatremia? | mannitol |
4 diuretics acting in the collecting duct | spirinalactone, eplernone, Amiloride, triamterene |
2 Diuretic the inhibits myocardial fibrosis? | spirinilactone, eplernone |
2 Diuretics used to treat Liddle Syndrome | amiloride and triampterine |
Diuretic used in nephrogenic diabetes insipidus? | thiazides |
Diuretic used to treat glaucoma, mountain sickness, and gout? | acetazolamide |
What type of diuretic can cause hyperkalemia and hyperkalemic metabolic acidosis | potassium sparing |
Which diuretics are potassium sparing | spironolactone, eplernone, amiloride, triamterene |
MOA of Amiloride and triamterene | inhibit ENaC in collecting ducts |
DOC for ascites and edema due to decreased plasma protein/hepatic failure? | spironolactone and eplerenone |
Diuretic that can cause torsade de pointes? | Thiazides |