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Restricting AP Trans
Presynaptic, Postsynaptic
Question | Answer |
---|---|
What is the significance of Synaptic Inhibition? | SUPRESSION of Spontaneous, Superfluous, Undesirable AP transmission |
In which pathways is Synaptic Inhibition most important? | Sensory and Motor Pathways |
What are 2 ways in which POSTsynaptic Inhibition occurs? | 1. release of Hyperpolarizing Neurotransmitter --> IPSP; 2. reduces/blocks Depolarizing effect of Excitatory Synapses - Stimulate Depolarization, Inhibit Hyperpolarization |
What are 2 ways in which PREsynaptic Inhibition occurs? | blocks Ca++ entry into Excitatory nerve terminal reducing release of Neurotransmitter substance --> Decrease IPSP |
What is an example of POSTsynaptic Inhibition? | Reciprocal Innervation of antagonistic muscles |
What is an example of PREsynaptic Inhibition? | Descending Inhibition or Habituation |
Where are Synaptic Inhibitors located? | NOT touching the POSTsynaptic Membrane, only the PREsynaptic Fiber |
What is Habituation? | PREsynaptic Inhibition - voluntary - receptor has not adapted, but Brain has |
When does Descending PREsynaptic Inhibition occur? | whenever there is Repetitive, Redundant information |
What is the significance of Habituation? | reduce distracting/monotanous information - allows concentration |