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pharm c.5-5 antiretr
pharm c.5-5 antiretrovirals
| Question | Answer |
|---|---|
| NRTIs--NUCLEOSIDE REVERSE TRANSCRIPTASE INHBITOR | WORK BY DECREASEING THE AMOUNT OF VIRUS IN THE BLOOD TO SPREAD TO OTHER HEALTY CELLS |
| NRTIs 1ST DRUG---RETROVIR | ZIDOVUDINE--(AZT) HIV |
| NRTIs---EMTRIVA | EMTRICITABINE--ONCE DAILY NO ALCOHOL |
| NRTIs---HIVID | ZALCITABINE---TAKE AC Q8H STORE IN AIRTIGHT CONTAINER (ORGINAL CONTAINER) 90 PER BOTTLE |
| NRTIs---ZIAGEN | ABACAVIR---ONE IF FEW MEDICATIONS THAT PENETRATE THE CNS(VIRUS CAN HIDE IN BRAIN) AVOID ALCOHOL COMPLETELY!!--PATIENT SHOULD BE CAUTIONED TO BE ON ALERT FOR POTENTIALLY LIFE THREATING REACTIONS--50% EXPERIENCE HYPERSENSITIVITY |
| NNRTI--NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | ACT ON A DIFFERENT SITE THAN THE NRTIs BUT PERFORM THE SAME ACTION--KEEPS IT FROM REPLCATING |
| NNRTIs---SUSTIVA | EFAVIRENZ--TAKE ONCE DAILY HS--AVOID HIGH FAT MEALS--MAY CAUSE DIZZINESS--MAY INDUCE VIVID DREAMS OR NIGHMARES |
| NNRTIs--VARAMUNE | NEVIRAPINE--EFFECT LIVER--MONITOR LIVER--DECREASES EFFECTIVENESS OF ORAL CONTRACEPTIVES----RIFAMPIN DECREASE ITS EFFECTIVENESS IN HIV PATIENTS WITH TB |
| NNRTIs--RESCRIPTOR | DELAVIRDINE--DO NOT TAKE WITH ANTIACIDS |
| PROTEASE INHIBITORS | INHIBIT THE REPLICATION OF THE HIV VIRUS. IT HAS CLASSIC SIDE EFFECTS OF REDISTRIBUTION OF BODY FAT CHARACTERIZED BY HUMPED BACK,(BUFFOLO HUMP) FACIAL WASTING AWAY, BREAST ENLARGEMENT, DEFICIENCY OF COAGULATION (DON'T CLOT VERY WELL) |
| PROTEASE INHIBITORS--CRISIVAN | INDINAVIR--DO NOT TAKE ST JOHNS WART, GRAPEFRUIT JUICE,HIGH FAT MEALS.--STORE IN ORGINAL CONTAINER--DRINK A LEAST 48 OUNCES OF WATER DAILY |
| PROTEASE INHIBITORS(COMBOS)--FORTOVASE, INVIRASE | SAQUINAVIR--AVOID SUN EXPOSURE |
| PROTEASE INHIBITORS ---NORVIR GIVEN WITH INVIRASE | RITONAVIR--TAKE W/FOOD,MAY ALTER TASTE, STORE ALL FORMS IN FRIDGE |
| PROTEASE INHIBITORS--REYATAZ | ATAZANAVIR--PATIENT WILL TURN A LITTLE YELLOW |
| PROTEASE INHIBITORS--APTIVUS - TO BE TAKEN WITH NORVIR | TIPRANAVIR--STORED IN FRIDGE, BLACK BOX WARNING FOR INTRACRANIAL HEMORRHAGES |
| PROTEASE INHIBITORS--PREZISTA | DARUNAVIR--GIVEN ACCELERATED APPROVAL FOR PATIENT W/RESISTANT STRAINS OF HIV--TAKE W/ FOOD |
| PROTEASE INHIBITORS(TWO NEW ONES)1ST--AGENERASE | AMPRENAVIR--CONTAINS HIGH DOSE OF VITIMIN E TO INCREASE ABSORPTION, CONTRAINDICATED IN PATIENT W/SULFA ALLERGIES, NUMBNESS AROUND MOUTH, NAUSEA |
| PROTEASE INHIBITORS--2ND--LEXIVA | FOSAMPRENAVIR--BETTER TOLERATED THA AGENERASE |
| FUSION INHIBITORS--ONLY INJECTABLE | PREVENT THE AIDS VIRUS FROM ENTERING THE IMMUNE CELLS(BIG CHANGE FROM TYPICAL TREATMENT OF HIV, GIVEN TO PATIENTS RESISTANT TO OLDER DRUGS |
| FUSION INHIBITORS--FUZEON | ENFUVIRTIDE--GIVEN SUBCUTANEOUSLY |
| CHEMOKINE CORECEPTORS--LAST MADE--SELZENTRY | MARAVIROC---PREVENTS VIRUS FROM ATTACHING TO IMMUNE CELLS, APPROVED FOR NEW STRAIN OF HIV(R5)--SIDE EFFECT- COUGH |
| INTEGRASE INHIBITORS | INHIBITS THE VIRUS FROM PRODUCING INTEGRASE WHICH IS NEEDED TO REPLICATE |
| INTEGRASE INHIBITORS---ISENTRESS | RALTEGRAVIR--REDUCES VIRAL LOAD AND INCREASE WBC COUNT,--RECEIVED PRIORITY REVIEW FROM FDA AND SHOULD BE USED IN COMBINATION W/OTHER ANTIRETROVIRALS |
| ANTIRETROVIRALS INTERACTIONS--SHOULD BE AVOIDED(1) | VIDEX WITH HIVID |
| ANTIRETROVIRALS INTERACTIONS--(2) | RETROVIR WITH ZERIT |
| ANTIRETROVIRALS INTERACTIONS--(3) | EPIVIR WITH HIVID |
| ANTIRETROVIRALS INTERACTIONS--(4) | ZERIT WITH HIVID |
| COMBO DRUGS---COMBIVIR | ZIDOVUDINE/LAMIVUDINE---NO CHILD UNDER 12 |
| COMBO DRUGS---TRIZIVIR | ZIDOVUDINE/LAMIVUDINE/ABACAVIR--(THREE DRUGS)--D/C IF FLU LIKE SYMTOMS ARISE |
| COMBO DRUGS---ATRIPLA | EFAVIRENZ,EMTRICITABINE,TENAFOVIR(3DRUGS)--BLACK BOX--FOR LACTIC ACIDOSIS--DISPENSE IN ORGINAL UNOPENED CONTAINER--CONTRAINDICATED IN 1ST TRIMESTER PREGNANCY |
| COMBO DRUGS--KALETRA | LOPINAVIR/RITONAVIR--N/V/D/PANCREATISIS--CONTAINS ALCOHOL-- |
| COMBO DRUGS---TRUVADA | EMTRICITABINE/TENOFOVIR--RECOMMENDED FOR POST EXPOSURE PROPHYLAXIS(P.E.P.)80% WITHIN FIRST 2 HOURS |
| COMBO DRUGS--EPZICOM | ABACAVIR/LAMIVUDINE---DISPENSE WITH WARNING CARD-IF PATIENT HAS TWO OR MORE OF FOLLOWING SYMTOMS: FEVER, RASH, N/V/D, FATIGUE, SOB, COUGH, SORE THROAT, THEN D/C |
| EXPOSURE TO HIV---POST-EXPOSURE PROPHYLAXIS | PEP---BEGIN THERAPY WITH IN 2 HR, DECREASE RISK OF INFECTION BY 80%---RETROVIR+EPIVIR+(CIXIVANOR VIRACEPT)---[BEFORE TRUVADA WAS MADE] |
Created by:
jddmmin7
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