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DIT adrenals
Question | Answer |
---|---|
3 beta hydroxysteroid dehydrogenase deficiency | inability to produce GCs, MCs, SHs; early death; excessive salt secretion in urine |
17 alpha hydroxylase deficiency | inability to produce GCs, SHs; increased MCs; =female with HTN |
11 beta hydroxylase deficiency | inability to produce aldosterone, GCs; increased deoxycorticosterone = HTN; increased SH = masculinization |
Adult male w/ elevated serum cortisol and signs of cushings. Cortisol is suppressed with high dose dexamethasone. | ACTH producing pituitary tumor |
A very tan child w/ a pale mother presents to your clinic and is found to be hypotensive. | 21 alpha hydroxylase def. |
21 beta hydroxylase deficiency | inability to produce GC (increased ACTH); inability to produce MC (hypotension); increased SH (masculinization) |