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DIT female repro
female reproduction quiz
Question | Answer |
---|---|
What do theca cells make that granulosa cells don't? | ANDROSTENEDIONE because they have 17 hydroxylase |
What do granulosa cells do? | they steal androstenedione from theca cell and use aromatase to convert it to ESTRADIOL |
What are the target cells of LH | Theca cells |
What are the target cells of FSH | Granulosa cells |
production of thick mucus that inhibits entry of sperm into the uterus | progesterone |
induces LH surge | estrogen |
uterine smooth muscle relaxation | progesterone |
follicle growth | estrogen |
maintenance of pregnancy | progesterone |
hepatic synthesis of transport proteins | estrogen |
withdrawal leads to menstruation | progesterone |
what drug would you give to inhibit prolactic secretion? | dopamine |
when does beta hCG appear in the urine during pregnancy? | 2 weeks after conception (4 weeks after LMP) |
what hormonal changes are seen during menopause? | decreased estrogen d2 increased FSH, LH and GNRH |
What is the underlying cause of PCOS? | increased LH leads to increased androgens leads to increased estrogens |
Clinical manifestations of PCOS | acne, hirsutism, amenorrhea, infertility, Obesity, Insulin resistance |
Treatment of PCOS | Gonadotropin analogs, OCPs, clomiphene, spironolactone, metformin |
produces AFP | yolk sac tumor |
estrogen secreting, causes precocious puberty | follicular cyst |
intraperitoneal accumulation of mucinous material | mucinous cystadenoma |
testosterone secreting, causes virilization | sertoli-leydig |
psammoma bodies | serous cystadenocarcinoma |
multiple different tissue types | teratoma |
lined with fallopian tube-like epithelium | serous cystadenoma |
ovarian tumor + ascites + hydrothorax | (meigs) fibromas |
call-exner bodies | granulosa cell tumor |
resembles bladder epithelium | brenner tumor |
elevated beta-hCG | choriocarcinoma, dysgerminoma |
risk factors for endometrial carcinoma | hypoplasia, increased estrogen, PCOS, obesity, unopposed HRT, age, tumor |
risk factors for ovarian cancer | family history, ovulation |
risk factors for cervical cancer | exposure to HPV |