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Med sheet Unit 1
Pharm II - Spring 2012
| Question | Answer |
|---|---|
| Acetaminophen trade name | Tylenol |
| Dosing of acetaminophen | 325-650mg q4-6 hrs |
| AEs of APAP? | Usu well-tol, hepatotox w/ OD or chronic high doses, nephropathy, anemia, blood dyscrasias |
| CI for APAP? | Severe hepatic impairment/active liver dz |
| Trade name ibuprofen? | Advil, Motrin |
| Dosing of ibuprofen? | 200-400mg q4-6hrs PO; 400-800mg q6hr IV |
| Ibuprofen AEs? | GI, renal, hematologic, hrt, hepatic, CNS |
| CIs for ibuprofen | Angioedema, bronchospasm w/ ASA or other NSAID; 3rd trimester preg |
| What can occur if ibuprofen/celebrex taken in 3rd trimester of preg? | Premature closure of ductus |
| Trade name of celecoxib? | Celebrex |
| Dosing of celecoxib? | 100 bid or 200mg qday for OA; 100-200mg bid for RA |
| AEs of celecoxib? | Less GI tox, potential for incrsd risk of heart events, renal, hepatic |
| CIs of celecoxib? | Allergy to sulfa-containing produx or ASA or other NSAIDS; 3rd trimester preg |
| Trade name of hydrocodone/APAP? | Vicodin, Lortab |
| Which class is vicodin? | C-III |
| What is the term used to refer to a med related to morphine? | Phenanthrene |
| Dosing for hydrocodone/APAP? | 1-2 PO q4-6hrs prn (5/500) |
| Max/day of hydrocodone/APAP? | 8/day |
| AEs of vicodin? | Drowsiness, N/V/C, pruritis |
| CIs for vicodin? | CYP3A4 substrate = can reach toxic levels w/ macrolides, ketoconazole, protease inhibs |
| Trade name of Tramadol? | Ultram |
| Class of Tramadol? | C-IV |
| Dosing of Tramadol? | 50-100mg q4-6hrs PO |
| Tramadol max/day? | 4g/day or >75yo = 3g/day |
| Onset of action for tramadol? | ~1hr |
| Pt w/ low CrCl taking vicodin..what is the max/day? | 2g/day |
| AEs of tramadol? | Drowsiness, N/V/C, pruritis |
| CIs with tramadol? | Sz d/o, anti-depress, anti-psychotic, w/macrolides, ketoconazole, protease inhibs (CYP3A4 substrate) |
| Naloxone trade name? | Narcan |
| Category of Naloxone? | Mu-ANTagonist |
| Use of narcan? | OD reversal |
| Dosing of narcan? | 0.4-1.2mg IV (onset ~2min)...may need to repeat q2-3mins |
| AE's of narcan? | Syncope, HA, insomnia, dizziness, N/V, injex site rxn |
| CI's of narcan? | Acute hepatitis, liver failure |
| Methotrexate trade name? | Rheumatrex |
| Methotrexate category? | Non-biologic DMARD |
| What does DMARD stand for? | Dz-mod anti-rheu drug |
| Gold std for RA? | Methotrexate |
| Use of methotrexate? | More severe/active RA |
| Dosing of methotrexate? | 7.5-20 mg/WEEK PO or Injex |
| Clin response of Methotrexate? | 1-2 months |
| AEs of methotrxate? | Stomatitis (inflamm of mucus membranes), nausea, diarrhea, alopecia, elevated LFTs, liver tox, thrombocytopenia, leukopenia, rare pulmonary and lymphproliferative tox |
| How can you possibly prevent alopecia with methotraxate use? | Concurrent use of folic acid |
| CI for methotrexate? | Preg or nursing, liver dz, kidney impairment, sig lung dz, alcohol abuse |
| What should be monitored with Methotrexate? | CBC, LFTs |
| If consumed in excess, what may decrs effectiveness of methotrexate? | Caffiene >180mg/day |
| Trade name of Hydroxychloroquine? | Plaquenil |
| AEs of Hydroxychlor? | Rash, diarrhea, abd cramps, retinal tox w/ high doses |
| What needs to be done periodically with those on Hydroxychlor? | Ophthalmic exams |
| CIs of hydroxychlor? | Long-term use in kids |
| Trade name of Etanercept? | Enbrel |
| Etanercept is what category? | Biolog-DMARD: Anti-TNF-alpha (used as monotherapy) |
| AEs of Etanercept? | HA, abd pain, resp tract infex, rhinitis, infex, lymphomas, may exacerbate or cause HF (WATCH FOR INFECTIONS!) |
| Prednisone trade name? | PredniSONE Intensol |
| Dosing for prednisone? | <7.5mg/day |
| AEs of prednisone? | HTN, hyperglycemia, cataracts, skin fragility, fluid retntion, wt gain, osteoporosis |
| CIs for prednisone? | Systemic fungal infex, admin of live or live-attentuated vaccines |
Created by:
streetsmarts
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