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PHARM CHARM II
ANS & SNS...
| Question | Answer |
|---|---|
| the space between the nerve and the tissue | synapse |
| neurons that go directly from the spinal cord to skeletal muscle make up the what? | Somatic Nervous System |
| Transmitter. A chemical released at all autonomic nervous system junctions EXCEPT at the post ganglionic sympathetic ending | Acetylcholine |
| Mediator/Transmitter. Found in the sympathetic nervous system in post ganglionic sites. | Norepinephrine |
| the body gets rid of acetylcholine using what? | acetyl cholinesterase |
| the body stops sympathetic activity by? | Reuptake |
| drugs that stim or mimic stimulation of the parasympathetic system are called? | Cholinergics |
| drugs that block parasympathetic system are? | anticholinergic |
| drugs that stim or mimic stim of the SYMPATHETIC system are called? | andrenergics |
| drugs that block the sympathetic system are called? | sympatholytics |
| drugs that act directly on the parasympathetic receptor to mimic action of stim of the parasympathetic system. | Cholinomimetics |
| used primarily in trmnt of glaucoma, eye disease charac by intraocular pressure, miosis (pupil constric), drains intraocular fluid | Pilocarpine |
| this drug side effects are: headache, difficulty with nught vision, nausea, eye pain, treats Sjogren's Syn | Pilocarpine |
| is used primarily post-operative to alleviate post-op and postpartum urinary retention and gastric distension. | Bethanechol [Urecholine] |
| Bethanechol contraindications are? | hyperthyroidism,asthma, Coronary Artery Disease, Bradycardia |
| what drug initially causes Abdominal discomfort, salivation, flushed skin, sweating, nausea, vomiting and miosis? | Bethanechol |
| What drug causes these toxic reactions? Intense cramping, diarrhea, urination, bradycardia and bronchoconstriction? | Bethanechol |
| the body stops sympathetic activity by? | Reuptake |
| drugs that stim or mimic stimulation of the parasympathetic system are called? | Cholinergics |
| drugs that block parasympathetic system are? | anticholinergic |
| drugs that stim or mimic stim of the SYMPATHETIC system are called? | andrenergics |
| drugs that block the sympathetic system are called? | sympatholytics |
| drugs that act directly on the parasympathetic receptor to mimic action of stim of the parasympathetic system. | Cholinomimetics |
| used primarily in trmnt of glaucoma, eye disease charac by intraocular pressure, miosis (pupil constric), drains intraocular fluid | Pilocarpine |
| this drug side effects are: headache, difficulty with nught vision, nausea, eye pain, treats Sjogren's Syn | Pilocarpine |
| is used primarily post-operative to alleviate post-op and postpartum urinary retention and gastric distension. | Bethanechol [Urecholine] |
| Bethanechol contraindications are? | hyperthyroidism,asthma, Coronary Artery Disease, Bradycardia |
| what drug initially causes Abdominal discomfort, salivation, flushed skin, sweating, nausea, miosis,vomiting, involuntary defecation and urination? | Bethanechol |
| What drug causes these toxic reactions? Intense cramping, diarrhea, urination, bradycardia and bronchoconstriction? | Bethanechol |
| which drug treats an excess of weakening skeletal musc. it treats myasthenia gravis.Helps patients swallow, open their mouth and breathe | Neostigmine [Prostigmin] |
| builds up acetylcholine to restore memory in Alzheimer's patients. For 3-4 months patient shows cognitive improvement.SE: swelling, diarrhea, gastric upset. | [Aricept] Donepezil |
| (prototype)decrease trachealsecretions and protect heart from vagal reflexes, usually given 1 hour b4 surgery, prior to anesthsia | Atropine |
| adverse affects of ______ include: tachycardia, decr gland secretions, decr GI motility, urinary retention,mydriasis, cyclopegia, and increased intraocular pressure | Atropine |
| twice a potent as atropine, has a longer duration of axn, no sedative effect | Glycopyrrolate [robunil] |
| an anticholinergic drug. a bronchodilator administered by aerosol inhalation. inhalation is less likely to produce cardiovas side effects. | Ipratropium [Atrovent} |
| prevention of motion sickness, releases the med slowly over 3 days | scopolamine transdermal |
| treatment of parkinson's disease, meds that block acetylcholine in the brain, drooling, shakiness, rigidity, cant move smoothly, lack dopamine | Benztropine [Cogentin] |
| the change in the ability of your eyes to accommodate | Cyclopegia |
| Anticholinergic drug dry up your nose secretions and stops your? | Runny Nose |
| what is mixed in to cause vasoconstriction, lasts longer acting on Alpha-1 receptors? | Epinephrine |
| acts on Alpha-2 receptors to shut off the release of norepinephrine? | Epinephrine |
| acts on beta-1 receptors to stimulate the heart | Epinephrine |
| when epinephrine is released in the Adrenal Medulla what happens? | Shot of Adrenaline |
| acts on beta-2 receptors to relax bronchial smooth muscle? | Epinephrine |
| Levophed, Levarterenol, Leave em dead. the main use is a vasopressor in treatment of hypotension. | Norepinephrine |
| primarily stimulates Alpha-1 receptors! Vasopressor in trtmnt of hypotension, little bronchodilating effect | Norepinephrine |
| what can slow down, speed up or do nothing to the heart and targets blood vessels? | Norepinephrine |
| treatment of bronchospasm in patients with asthma | [Ventolin] Albuterol |
| released by the adrenal gland, called catecholamine | epinephrine |
| injected into ishemic tissue that has been damaged. keeps Levophed from causing tissue damage. treats sever tachycardia. treats hypertensive crisis.decr BP slowly. | Phentolamine[Regitine] |
| doesn't effect beta receptors. treats hypotension. vasoconstriction. causes reflex bradycardia. can be topical.PURE alpha agonist. | Phenylephrine[Neo-Synephrine] |
| topically, orally it is used as a nasal decongestant in trtmnt of sinusitis & rhinitis. Contraind: heart dis, hypertension and diabetes. | Phenylephrine [Neo-Synephrine] |
| relatively pure beta-2 agonist. some effect on beta-1recep. acute asthma attack, relaxes bronchial smooth muscle, may incr heart rate, lowers BR, reflex incr heart rate, musc tremor | [Proventil} Albuterol |
| causes vasodilation. primarily in kidney. catecholamine. supports CHF and other hypotensive conditions. causes release of norepinephrine. | Dopamine |
| indirect acting drug that causes release of norepinephrine, targets blood vessels, absorbed in the gut, crosses the BBB, stays in body longer, not metab by COMT, found in app supress, amphetamines and decongestives | Ephedrine |
| treats ADHD | Methylphenidate [Ritalin] |
| What is the mechanism of action in ____? treats hypertension bradycardia, dilation of blood vessels, fall in BP | Clonidine [Catapres] |
| what drug produces these side effects? Water retention,sig reductions in BP, rebound hypertension-sudden w/drawal of drugs | Clonidine |
| they block alpha-1 receptors causing vasodilation in the skin, fall in BP, treats hypertension, BPH(benign prostatic hyperplasia) and seldomly causes tachycardia | [Minipress] Prazosin |
| how do you avoid first dose effect? | take first dose at bedtime |
| This treats BPH by relaxing smooth muscle in the prostate and bladder neck? | Minipress |
| is not an Alpha blocker but an inhibitor of cyclic guanosine monphosphate. Specific for a certain enzyme found in corpus cavernosum, thus imp erectile response to sexual stimulation. | [Viagra] |
| lowers BP and is contraindicated with organic nitrates or nitroglycerin. Similar drugs are Cialis and Levitra. | {Viagra} |
| it blocks beta-1 in the heart, beta-2 in smooth musc, slows the heart, may precip an asthma attack, so ashtma patients are contraind | Propranolol [Inderal] |
| cardio selective beta blocker, low doses block beta-1, no effect in beta-2. slows heart, decr contractility. can precip asthma attack | Metoprolol [Toprol XL] |
| alpha/beta blocker developed as an antihypertensive but also used in CHF. They cause orthostatic hypotension. | Labetalol [Normodyne] |
| a cardioselective blocker with a fast onset and short duration. used in IV for supraventricular tachycardia.ICU | Esmolol[Brevibloc] |
| decr in formation of AQ humor. used an eye drop in glaucoma trmnt, beta blocker, enough cab be abs through the ventric canal in eye and cause sys effect. slows the heart, asthma can worsen | Timolo [Timoptic] |
| Nicotine is used as a ? | Transdermal patch |
| chewing gum that releases Nicotine the harder and faster you chew. use is for ppl trying to stop smoking. | Nicorette |
| an antidepressant which is first non-nicotine drug used to assist smokers to stop smoking. | [Zyban]Bupropion |
| an oral drug that binds to the nicotinic receptor blocking nicotine from binding to the receptor but leads to the release of dopamine. | [Chantix] |
| side effects of this drug include nausea, sleep disturbances, headaches, and abnormal dreams. | [Chantix] |
| blocks acetylcholine receptor sites atneuromuscular junctions. skeletal muscle relaxant, there are 2 types! | Neuromuscular blockers |
| sits on thereceptorsite, prev acetylcholine immed, red skeletal muscle activity, competitive antagonist, prototypre drug | Tubocurarine |
| depolarizing drug, 2 acetylcholine molec stuck together, sits on receptor sites causing a refractory period, muscle twitch, CANNOT be destroyed by cholinesterase, fast acting drug | Succinylcholine |
| during the refractory period the muscles relax, used during drug intubation, tube is placed in trachea/windpipe | Succinylcholine |
Created by:
boomer_bevo
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