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PHYS T1 Review

Review material from Test 1 PART II

QuestionAnswer
Flux is? What does it mean for net flux to be 0? Amount of material crossing a surface /time. Net flux = 0 when equilliburium is reached
What is the net flux equation? Kp (perm const) * Area (Cout - Cin)
What is the diffusion dependent upon? 1. Concentration 2. Temp 3. Mass 4. Surface Area 5. Medium
Which ones have an indirect releationship with net flux? Mass
What can diffuse through lipid bi-layer more easily? Polar or non-polar? Non-polar
What electrical phenomena affects ion diffusion? Membrane potential
What the heck does the above mean??? It means that since most cells are (--), we'll try to get (+) in, too to balance it all out
What are the two components of the electrochemical gradient? Concentration and electrical differences
Why can't AA and and glucose diffuse through lipid bilayer? Because it is too polar and too big
So lucy lou, what do we do? TRANsporters!
What are these like? PACMAN
What are the two types? Facilated and active
How fast are transporter proteins? SLOW, b/c unlike diffusion, they can become saturated!!!
What is transported in this way?? Glucose
Primary Active Transport energy it needs is: ATPase
What is transported using primary active transport? Na/K , Ca, H+, and H+/K+
How does secondary active transport work w/ what kind of energy? Explain: Ion concentration gradient; movmenet of stuff from hi to low conc. provides energy for this secondary process
Can water diffuse across a cell membrane considering it is polar? yeah, b/c it is small
What is mostly INSIDE (Intracellular)? K+ and organic solutions
OUTSIDE (EXTRACELL) Na/ Cl-
ISOTONIC size difference? Same
Hypertonic? Cell shrinks
Hypotonic? Cell swells
How can stuff diffuse across skin? Use the terms endo/exo/desmosomes Paracellular pathway (desmo) or transcellular pathway (across; endo/exo)
LECTURE 7 LECTURE 7
What are the four parts of the neuron? Function of each? Cell body (nucleus), dendrites (receive info), axon (single; transmits info to neurons), and axon terminal (neurotransm)
What is the nodes of ranvier? Gaps in myelination of axon
What DON'T afferent neurons contain? NO DENDRITES
Where are most portions located? OUTSIDE CNS
EFFERENT has most portions where? Where's the axon? Most portions in, but axon is outside CNS
Interneurons are located? IN CNS
What are glial cells? form myelin, neurons need them
What forms myelin in CNS? PNS? Oligodendrocytes in CNS; schwann int he other
Can neurons in CNS divide? What about PNS? No in CNS; yes in PNS
What phenomena helps maintain membrane potential? Sodium potaisum pump: 3 NA OUT, 2 K IN
What is the resting membrane potential in Neuron? -70
Where does the current in an AP travel along in the neuron? Along the axon
What is a graded potential? Vs. AP? Doesn't reach AXON at all. AP goes all along axon
Overshoot? Inside of cell becomes +
Repolarized? Go back to resting
What induces DEpolarization? Sodium getting into cell (making it less negative)
Hyperolarized is induced by? becomes more negative by K+ flowing otu of cell
LECTURE 8 LECTURE 8
Comapre theWhen the neuron membrane reaches threshold potential, compare teh size of the AP generated if I had burned my hand vs. felt a change in temp? Same SIZE despite strenght of stimulus
Hyperpolarization involes the cllsoing of what channel and opening of what channel? Sodium closes, potasium opens
Why does potasium open? Restore membrane potential
How does the size of the AP decrease as it is propeganted along the axon? IT DOESN'T
What does the velocity of the AP depend on? Fiber diameter and myelination
SNAPSES SYNAPSES
An excitatory synapse brings teh membrane of the presynaptic cell closer to threshold. T or F? FALSE, it is the POSTsynaptic
What influences whether a postsynaptic cell fires APs? Active synpases and whether they're excting or inhibitory
What happens when the AP reaches the end of the presynpatic neuron? Depolarize, calcium channels open, and calcium gets into axon terminal
What happens after ca is in axon terminal? Vesicles fuse w/ PM and release contents 5. NT gets with post-synpatic cell-->activate its recetprs 6. Open ion channels or close them in postsynaptic PM
Excitory synapses open what channels? Inhibitory synapses open what channels Excite: Na/K. Inhibit: Open Cl-/K
Neurotransmitters cause? EPSPs and IPSPs
NEUROTRANSMITTERS AND NEUROMODULATORS STUFF TO KNOW!!!
Acetylcholine (Ach) function in PNS. What abuot CNS? PNS: Skelatal muscles. CNS: role in learning
What does nicotinic vs. musscarininc ach do? Nicotinic: ion channel. Muscarinic: W/ G-protein
Biogenic amines from amino acids are: serotinin histamine, catecholamines
What are exampels of catecholaimines? NE:, EPI, and DOPAMINE
Alpha adrenergic receptor is activated by? cAM<P second messengers or impacts Ca/K+ channels
Beta adrenergic: cAMP second messenger
Function of seratonin? IN CNS OR PNS? Neuromodulator (in CNS)
What are excitory aminio acids in teh CNS? and short role? Glutamate and aspartate (role in learning)
What are inhibitory amino acids in CNS? GABA and Glyucine
What is an example of a neuropeptide? Important with? Endogenous opioids; runner's high
LECTURE 9 LECTURE 9
Nerve: Nerve fibers in PNS
Tract: Nerves in CNS
Ganglion: Bodies in PNS
Nuclei: BODIES IN CNS
Spinal cord has gray matter containnig? What about white matter? Graymatter has cell bodies, whereas white matter has axons in tracts (myelinated)
What does the meddula oblongata contain that is really essential for life? Reticular formation
When does the cerebellum develop? What does it have a role in? AFTER birth. role in posture, movement, memory
What is the lymbic system? What disease most affects it? forebrain associated with learning and emotions; impacted by alzhemiers disease
What kind of nerve fibers are in DRG? BOTH afferent and efferent neurons
Somatic fibers release and act upon? Ach and act on skeletal muscles
Created by: talkglitter2486
 

 



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