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MICRO4
BACTERIAL Cardiovascular and Lymphatic Diseases
| Question | Answer |
|---|---|
| CHARACTERISTICS OF CARDIO AND LYMPHATIC | CHARACTERISTICS OF CARDIO AND LYMPHATIC |
| ENDOCARDITIS | ENDOCARDITIS |
| What are some predispositions for endocarditis? | ANY Different heart strucutres |
| What condition can endocarditis arise from? | Rheumatic fever |
| What does the bacteria need first to affect you? | Bacteremia to stick in valves or damaged area |
| What is this called? | biofilm formation |
| Give examples of procedures that would lead to ssuch an exposure? | surgeory, peircings |
| What are the two kinds of endocarditis? | Sub acute and acute |
| What are characterisitcis sub acute? | Slow development, mild fever daily for months before symptoms, and heart murmor |
| What is acute endocarditis? | Rapid onset high fever |
| What is the furthest progressed symptom/ | Splinter hemorrhages on fingernails |
| BACTERIAL CAUSES OF CARDIOVASCULAR AND LYMPHATIC DISEASE | BACTERIAL CAUSES OF CARDIO AND LYMPHATIC |
| What does streptococcus pyogenes cause? | Group A strep |
| ID it: Why is it Beta hymolytic? | Gram positive cocci in chains. It is beta hemolytic b/c of exotoxin |
| What virulence factors doe s it have? | Capsule, M protein, streptolysins O, streptokinases, hyaluronidase, DNAse, Leukocidins, Erythrogenic toxins |
| What does streptolysin 0 do? What do streptokinases do? What is spit out after DNAse works? What are erythrogenic toxins? | Streptolysin O, which lyses WBC; streptokinases break down clots; neutrophil; Scarlet fever |
| What are some diseases caused by streptococcus pyogenes? | puerperal sepsis, lemierre's syndrome, rheumatic fever, |
| What is puerperal sespsi also known as? What is it? How is it transmitted? How frequent is it? | Childhood fever; nasocomial infection of uterus after delivery; transmitted by hospital staff; RARE |
| Lemierre's syndrom is caused by? How does it work? How common | Caused by abscess near tonsils secondary to strep infection. The abscess migrates to jugular vein--> clot (thrombosis), then clot goes to lungs or heart, which is FATAL; Increasingly more common |
| What does it mean for it to be secondary? | Not directly due to strep |
| What bacteria causes lemierre's syndrome? Aerobe or anerobe? | Fusobacterium |
| When would one develop RHEUMATIC FEVER? | After strep throat |
| What is rheumatic fever?? | Our immune response gone wrong to strep throat |
| What is the ACTIVE infection associated with it? | NO ACTIVE infection |
| What are some symptoms of rhematic fever? What does it lead to? Why? | Arthritis, fever-->>causes heart damage b/c of M protein |
| HOw do you diagnose rheumatic fever: Catalase and hemolysis? | Beta-hemolytic on blood agar and CATALASE NEGATIVE |
| What group is it specific for? | A carb |
| How do you prevent it? | Treat strep throat, wash hands |
| ID Endotoxic shock | Gram-negative sepsis |
| **What is GRAM-NEGATIVE SEPSIS the leading causes of? | Septic shock |
| What are the symptoms of shock? | Increased heart rate, decrease temp and bp |
| What are treatments for GRAM NEGATIVE SPSIS? Why? | NOT Antibiotics!! If you kill bacteria, you release endotoxin in the form of LPS-->shock!! |
| STAPHLOCOCCUS AUEREUS | STAPH AUREUS |
| What duseases does it cause? What is its resistance? | Sepsis and endocarditis; MRSA |
| What kin dof pathogen is it? Where would you find it? | Opportunitistic nasocomial pathogen in tooth extractions |
| Hemolysis? Catalase? Coagulase? | Beta hemolytic, catalse positive, coagulase positive |
| What is ALL staph catalase? | POSITVE |
| LYME DISEASE | LYME DISEASE |
| What bacteria causes lyme disease? | borrelia burgdorferi |
| Shape? | Spriochete |
| NOTE FIGURE 23.14: What is the number one indicator of lyme disease? | NOTE FIGURE 23.14: RASH |
| What is the vector and reservoir for it? | Deer tick is the vector, but reservoir is filed mice |
| What is a treatment? Prevention? | antibiotics; prevent with control of tick population |
| TYPHUS FEVER | TYPHUS FEVER |
| What is the organism that causes this? | Rickettsia prowazekii |
| ID IT: Where does it infect? | Obligate intracellular; infects endothelial cells of vascular system |
| What is the vector? reservoir? | Anthropod vector; rat reservoir |
| What is the Tick-borne typhus organism? AKA? | Rickettsia rickettsii; rocky mountain spotted fever |
| Disease involves what? Causes what? | Rash everywhere but TRUNK of body; causes fever, headache |
| What two important things must be remembered about typhus fever? | Obligate intracelluar growth and is not culturable |
Created by:
talkglitter2486