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ID for CK
Infectious Disease for Step 2 CK
Question | Answer |
---|---|
PCN G, VK and benzathine covers which bugs? | Viridans group strep, strep pyo, oral anerobes, syphilis, leptospira |
Ampicillin and amoxicillin cover which bugs? | Viridans group strep, strep pyo, oral anerobes, syphilis, leptospira, e. coli, lymes, a few other G- bacilli |
Amoxicillin G - coverage? | HELPS: H flu, e coli, listeria, proteus, Salmonella |
PCN G, VK, and benzathins, Amox and Amp are best initial therapy for what diseases? | OM, Dental infections, endocarditis prophy, lymes confined to rash/joint/CN 7, UTI in preggers, Listeria, Enterococcal infections |
Penicillinase-resistant PCN: ox, clox, diclox and naf are used for what? | Skin infectious (cellulitits, impetigo, erysipelas), staph endocarditis, staph meningitis, staph bacteremia, osteomyelitis and septic arthritis if sensitive, NOT for MRSA or meth resistant enterococcus |
What is the side effect of Methicillin that prevents it from being used? | Allergic interstitial nephritis |
Pipercillin, ticarcillin, azlocillin, mezlocillin cover which bugs? | Gram negative bacilli (ex: E coli, proteus, H flu, legionella, pseudamonas, enterobacter cloacae, serratia, H. pylori, salmonella enteriditis, salmonella typhi), use with b-lactamase inhibitor |
Pipercillin, ticarcillin, azlocillin and mezlocillin are best initial therapy for which diseases? | Cholecystitis, ascnding cholangitis, pylenophritis, bactermeia, hospital and ventilator associated pneumonia, neutropenia and fever; use with b-lactamase inhibitor |
If a bug is sensitive to pipercillin, ticarcillin, azlocillin or mezlocillin, why would you not use them? | Single organism infectious, use narrower spectrum, if you do use these, use with b-lactamase inhibitor |
What bugs do all cephalosporins cover? | Group A, B and C strep, viridans group strep, E. Coli, Klebsiella and Proteus mirabilis |
What bugs are resistant to all cephalosporins? | Listeria, MRSA and Enterococcus |
What do you use if there is a rash allergy to penicilins? | Cephalosporins |
What do you use if there is anyphilaxis to penicillins? | Non-beta lactam |
What are the first generation cephalosporins? | Cefazolin, Cephalexin, Cephradrine, Cefadroxyl |
Which bugs are first generation cephalosporins used to cover? | Staph (MSSA), Strep (except Enterococcus), some gram negative bacilli (NOT pseudamonas) |
Which diseases are first generation cephalosporins able to cover? | Osteomyelitis, septic arthritis, endocarditis, cellulitis |
What are the second generation cephalosporins? | Cefotetan, Cefoxitin, Cefaclor, Cefprozil, Cefuroxime, Loracarbef |
What are second generation cephalosporins used to treats? | Staph (MSSA), Strep (except Enterococcus), some gram negative bacilli (NOT pseudamonas), additional anerobe and more G- bacilli |
What is special about Cefotetan or cefoxitin? | Best initial therapy for PID in combo with Doxycyclin, increased risk of bleeding (due to depletion of prothrombin), disulfiram like reaction when used with alcohol |
What is special about Cefuroxime, Loracarbef, Cefprozil, and Cefaclor? | Cover resiratory infections like bronchitis, otitis media, and sinusitis |
What are the third generation cephalosporins? | Ceftriaxone, Cefotaxime, Ceftazidime |
What is special about Ceftriaxone? | First line for pneumococcus (including partially insensitive organisms) in meningitis, CAP (combo with macrolide), GC, lyme of heart or brain; can cause iadequate biliary metabolism |
Who should Ceftriaxone be avoided in and why? | Neonates due to impaired biliary metabolism |
What is special about Cefotaxime? | Superior to ceftriaxone in neonates and can be used for spontaenous bacterial peritonitis |
What is special about Ceftazidime? | Pseudamonal coverage |
What is the fourth generation cephalosporin? | Cefepime |
What is special about Cefepime? | Better staph coverage then 3rd, used for neutropenia and fever, and ventilator-associated pneumonia. |