click below
click below
Normal Size Small Size show me how
PHYS3
Circulation: Overview
| Question | Answer |
|---|---|
| Why is the circulatory system necessary? | To transport molecules rapdily over long distance |
| What does the circulatory system transfer materials across? | between internal cells and the body's surface and between the various specialized tissues and organs. |
| What comprises the circulatory systeM | Blood, set of interconnected tubes through which blood flows, and a pump that produces the flow |
| What are the tubes? | Blood vessels |
| What is the pump? | The heart |
| What composes the blood? | Cells, plasma, and erythrocytes |
| What are the three cell types in blood? | Erythrocytes, leukocytes and platelets |
| What is the plasma? | Liquid in which cells are suspended. |
| What is plasma made of? | Proteiins, nutrients, and metabolic end products, hormones, and mineral electrolytes |
| What percent of blood cells are erythrocytes? | The most!! |
| What do erythrocytes contain? | Hemoglobin |
| What is it? | Oxygen binding protien made of heme and globin |
| Where does the oxygen bind? | On the iron in heme |
| Where are erythrocytes produced? | In bone marrow |
| Where are they destroyed? | LIver and spleen |
| What is essential for erythrocyte formation? | Iron, folic acid, vitamin B12 |
| What is erythropoietin? | Hormone produced in kidneys in response to low oxygen supply. |
| What does it stimulate? | Erythrocyte differentiation and production by bone marrow |
| What is anemia? | A decrease in total number of erythrocytes, and a diminished concentration of hemoglobin per erythrocyte |
| What are some potential causes? | Dietary deficiency, bone marrow failure, blood loss, and decreased erythropoietin. |
| What are the three types of leukocytes? | Polymorphonuclear granulocytes, monocytes, and lymphocytes |
| What are polymorph granulocytes? | Neutrophils, eosinophils and basophils |
| What are platelets? | Cell fragments essential for blood clotting |
| Where do all blood cells descend from? | Pluripotent hematopoietic stem cells from bone marrow |
| ^___RELAX_____^ | ^____RELAX____^ |
| What does the cardiovascular system consist of? | Two circuits, both originating and terminating in the heart |
| What is the heart divided into? | Longitudinally into two functional halves, each containing two chambers |
| What are th e two heart chambers? | Atrium and ventricle |
| What is teh atrium? | Empties into the ventricle |
| What is the ventricle? | EJECTS into arterial circulation |
| What are the two heart circuits? | Pulmonary and systemic circulation |
| What is the pulmonary circulation? | Blood travels from right ventricle to the lungs and then to the LA |
| What is the sytemic circulation? | Blood travels from LV to all organs and tissues other than the lungs andthen to the right atrium |
| Where do arteries carry blood? Generally, where do veins carry blood? | Away from the heart; to the heart |
| SYSTEMIC CIRCULATION | SYSTEMIC CIRCULATION |
| Aorta: | The large artery leaving the left heart |
| Superior and inferior Vena cava: | The large veins emptying into the right heart |
| What are the vessels in the pulmonary circulation? | Pulmonary trunk and the four pulmonary veins |
| What does microcirculation consist of? | Vessels between arteries and veins. |
| What are those vessels? | Arterioles, capillaries, and venules |
| DISTRIBUTION OF SYTEMIC BLOOD FLOW | DISTRIBUTION OF SYSTEMIC BLOOD FLOW |
| PRESSURE, FLOW, AND RESISTANCE | PRESSURE, FLOW, AND RESISTANCE |
| Pressure: | Force exerted by the blood |
| Blood flow related to pressure: | From a region of higher pressure to one of lower pressure |
| Units of measurement of blood flow? | Volume per unit of time (liters/ min) |
| Resistance: | Indication of how difficult it is for blood to flow between two points at any given pressure difference |
| What is the relationship of flow to resistance? | Flow is inversely proportional to resistance |
| What is the basic equation for calculating resistance? | Pressure = Flow x resistance |
| What does resistance determine? | SEE BELOW |
| What is ressitance directly proportional to? | Viscosity of a fluid and length of the tube |
| What is it inversely proportional to? | Fourth power of the tube's radius |
| What is a major variable for controlling changes in resistance? | Tube's radius to the fourth power |
| SEE EQUATION | SEE EQUATION--P. 201 |