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MICRO2

Infectious Disease

QuestionAnswer
PROCESS OF COLONIZATION PROCESS OF COLONIZATION
What must first occur before an organism can start making trouble? It must first stick by evading host defense
What is the process of colonization? List steps Site specificity, adherence, and microbe growth
What influences adhesion? Chemical specificity
Define microbiota and carrier state: Microbiota: flora; carrier state: most people will get disease, but some won't
Give examples of sterile sites: Our brain, most of our body
MICROBE-HOST RELATIONSHIP MICROBE HOST RELATIONSHIP
DEFINE NON-PARASITES: Won't drain you of resource
Give examples: Saphrocytes, Mutalism, commensial microbes
What are saphrocytes? Live on dead stuff
Mutalism: Both benifit
Commensial microbes: Host not affected
Systemic: Spread by blood of lymphatic system
Bacteremia: Presence of bacteria in blodd that aren't growing
Septacimia: Bacteria growing in our bodd
Virelemia; Reproducing viruses in blood
Toximia: Toxin in blood
PROCESS OF DISEASE PROCESS OF DISEASE
Adhesion; Attachment molecule
HARMFUL MICROBIAL PRODUCTS HARMFUL MICROBIAL PRODUCTS
What are some virulence factors that are produces by the microbe? Endotoxins and exotoxins
What are endotoxins? Carbs or lipids
What cell type releases them? Give example: Gram --; like the LPS and lipid A
What is an assay of endotoxin? LAL Assay in lab--from horseshoe crab
Compositon of exo vs. endo? Protein vs. carbs and lipids
Production of exo vs. endo? Active release vs. component of cell
Target of exo vs. endo? Specific (enzyme) vs. general (immune response)
Stability of exo vs. endo? Not stable vs. very stable
From which cell type are exotoxins released? Gram +
From which cell types are endotoxins released? Gram --
Do we want to release endotoxins: NO NO NO NO NO!!!!
What do fungi and parasites lead to? Allergic reactions
Toxicity of Exo vs. endo High tox vs. low tox
So, how much of a dose do you need for exo vs. endo? low vs. high dose
Fever response of exo vs. endo: No fever vs. fever
Created by: talkglitter2486
 

 



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