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Miles Pharmacology 2
Pharmocology exam 1 study guide
| Question | Answer |
|---|---|
| What are the three phrases of drug action and what happens in each | smal gropu of healthy volunteers-onset of drug action elimination side effects, treatment in small group with disease- 100-300 is drug safe, large multicenter studies 1000-3000 is drug better than regular treatment control group receives regular treatment |
| when was the original food and drug act passed? | 1906 USP and NF were given official status |
| When was the current food and drug act passed? | 1938 food drug and cosmetic act becomes law, it protects the public |
| What is the FDA's role in sale and control of drug use | power to approve or deny new drug applications and ensure compliance via inspections |
| define Affinity | cell recipient |
| define efficacy | how well a drug produces its desired effect |
| define agonist | drug that binds to a specific receptor broducing a stimulatory response |
| define antagonist | drug that prevents an agonist from binding to its specific receptor |
| define receptor site | The site either on a cell surface or inside cell that binds with a specific substance or drug |
| define potency | amount of a drug that must be given in order to produce a particular response |
| define half life | major determining factor of the length of a drugs action in the body |
| define anaphylactic shock | severe sudden allergic reaction that may be life-threatening |
| what is informed consent | |
| list different receptor types commonly acted upon by RC drugs | lipid soluble (Corticosteroids), transmembrane receptor (Albuterol) |
| be able to tell how G protein receptors work | start effector system, produces second messenger that causese cell response |
| what is a side effect | effects that were not necessarily intended |
| what is the advantage of the aerosol route of drug administration | deliver medication to the immediate site of action with few systemic adverse effects |
| what things affect deposition of aerosol drugs in the lung | |
| give causes of medication errors | manufacturing errors ,prescribing errors, administration errors |
| list rights of drug adminstration | right patient, right drug, right dose, right route, right time, right technique, right documentation |
| what do you chart after nebulizer therapy | |
| review generic and trade names of adrenergic drugs | |
| review different routes of drug admnistration | enteral via gi tract, sublingual, buccal, Parenteral injection, topical, transdermal, inhalation, nasal, rectal, vaginal, eyes, ears |
| review different names drug goes through during approval | chemical name-unique one of a kind often complicated and lengthy, generic name- less complicated there is only one generic name for each drug, trade name- created by a namufacturer to establish a product name that belongs to them |
| define pharmacology | study of drugs including their origin properties and interactions with living organisms |
| define respiratory care pharmacology | application of pharmacology to the treament of cardiopulmonary disease |
| what does MAR stand for | Medication administration records |
| define therapeutic classification of drugs | What condition the drug is used to treat |
| define pharmacological classification of drugs | how the drug works in the body's systems, tiessues, and molecues |
| what is an aerosol | liquid or fine powder that is sprayed in a fine mist |
| what are the three common delivery devices for aerosol drug administration | nebulizers, dry powder inhalers (DPI's), Metered dose inhalers (MDI's) |
| what is the most common source of therapeutic drugs today | |
| what factors affect drug action | weight, age, sex, race |
| which receptors are found in the sympathetic nervous system and what do they do when stimulated | |
| which receptors are found in the parasympathetic nervous system and what do they do when stimulated | nicotinic, muscarinic |
| define adrenergic bronchodilators | |
| define anticholinergic bronchodilators | |
| list anticholinergic bronchodilators | |
| give anticholinergic bronchodilators side effects | |
| give anicholinergic bronchodilators clinical use | |
| list adrenergic bronchodilators | |
| give adrenergic bronchodilators side effects | |
| give adrenergic bronchodilators clinical uses | |
| list adrenergic bronchodilators | |
| give antiadrenergic bronchodilators side effects | |
| give antiadrenergic bronchodilators clinical uses | |
| what is the dosage for giving albuterol in a continuous nebulizer | |
| how do we asses effectiveness of beta 2 bronchodilators | |
| how are peak flow meters used | |
| how do we get percentage of predicted for peak flow readings | |
| how are green, yellow and red zones determined for peak flow readings | |
| how do you find a patients personal best peak flow reading | |
| what distributes drugs throughout the body | bloodstream |
| what organ metabolizes drugs | liver |
| what organ eliminates drugs from the body | kidney |
| what will happen to drug elimination of drugs if a patient has liver or kidney disease | |
| define tolerance | the development of resistance to a drugs effects to the degree that does must be raised continually to acheive the desired response |
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