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U5: Pharynx/Esoph
Digestive System Part III: Pharynx, Esophagus, Stomach
Question | Answer |
---|---|
Pharynx | consists or nasopharynx, oropharynx, laryngopharynx; however, nasopharynx solely part of respiratory tract; does not process food in any way, just passes it to esophagus |
Oropharynx | lined w/ stratified squamous epithelium for protection against abrasive food; receives food and fluid from oral cavity & air from nasopharynx; passageway for both digestive and respiratory tracts; palatine tonsils located in lateral aspect of the fauces |
Laryngopharynx | lined w/ stratified squamous epithelium for protection against abrasive food; receives fluid, food, air from oropharynx, so passageway for both digestive and respiratory tracts; esophagus begins at inferior border, from which it receives food and fluid |
Pharyngeal constrictor muscles | encircle pharynx and function to squeeze bolus into esophagus during swallowing |
Esophagus | about 10” long muscular tube; extends from laryngopharynx, through posterior mediastinum, into abdominal cavity through opening in diaphragm (esophageal hiatus) and empties into stomach via cardiac orifice |
Cardiac orifice | esophagus opening into stomach |
Cardiac/gastroesophageal sphincter | scanty, weak ring of smooth muscle at junction of esophagus and stomach; helps prevent backflow of acidic gastric juice into esophagus |
Hiatal hernia | condition in which small portion superior aspect of stomach pushes thru enlarged esophageal hiatus, following a weakening of diaphragmatic muscle fibers around edge of hiatus; little bit of stomach is above level of diaphragm & actually in thoracic cavity |
Heartburn | pain due to regurgitated acidic stomach juice irritating the esophageal mucosa |
Gastroesophageal reflux disease (GERD) | hiatal hernia and persistant regurgitation of gastric juice and heartburn are associated w/ this condition |
Stratified squamous epithelium | tissue lining esophagus |
Skeletal muscle in superior third, mixture of skeletal and smooth in middle third, smooth muscle in lower third | arrangement of muscularis externa of esophagus |
Stomach | J-shaped organ; extends from esophagus to duodenum; widest part of alimentary canal; temp. storage tank; churns food into chyme; begins breakdown of food proteins w/ pepsin; absorbs water, alcohol, aspirin; food will remain in this organ for about 4 hours |
Chyme | thick, soupy mixture of partially digested food produced by activity of stomach |
Pepsin | stomach enzyme that begins breakdown of food proteins |
Extends from esophagus to duodenum of small intestine; located in upper left abdominal cavity, directly inferior to diaphragm, anterior to pancreas | location of stomach |
Cardiac, fundic, body, pyloric | regions of stomach |
Cardiac region of stomach (cardia) | portion of stomach to which esophagus is attached |
Fundic region of stomach (fundus) | dome-shaped, highest region of stomach, tucked under diaphragm |
Body of stomach | middle portion |
Pyloric region of stomach | funnel-shaped, terminal (distal) region that attaches to duodenum of small intestine; located at junction of organs is pyloric sphincter |
Pyloric sphincter/valve | located at junction of stomach and duodenum of small intestine; controls entry of chyme into the duodenum |
Greater curvature of stomach | convex left margin of stomach |
Lesser curvature of stomach | smaller, concave right margin of stomach |
Rugae | folds/wrinkles of mucosa of internal surface of empty stomach which flatten as stomach fills; resulting expansion accommodates increasing quantity of food within stomach |
Mucosa, submucosa, muscularis externa, serosa/visceral peritoneum | four layers of stomach wall |
Lining epithelium of mucosa | consists of simple columnar epithelium; has many mucus-producing cells for protection of stomach lining from its own harsh gastric juices via millions of tiny gastric glands containing mucus-producing cells, parietal/oxyntic cells, & chief/zymogenic cells |
Parietal/oxyntic cells | cells in gastric glands of mucosa; produce stomach’s hydrochloric acid (HCl) and instrinsic factor. |
Gastric intrinsic factor | produced by parietal/oxyntic cells; needed for absorption of vitamin B12 by small intestine, which is needed for RBC production |
Chief/zymogenic cells | cells in gastric glands of mucosa; make and secrete pepsinogen, which is activated to pepsin when it encounters stomach’s hydrochloric acid |
Enteroendocrine cells | group of cells in stomach and small intestine lining epithelium that secrete hormones that affect digestive activity |
Circular, longitudinal, oblique | three layers of smooth muscle instead of usual 2; third layer gives stomach greater churning/mixing power |
Peptic ulcers | crater-like erosions of mucosa of stomach/duodenum/esophagus; most occur in duodenum & stomach; vast majority are usually caused by acid-resistant helicobacter pylori which primarily inhabits stomach; can usually be cured by antibiotics |
Helicobacter pylori | acid-resistant bacterium that binds specifically to gastric epithelium and induces over-secretion of hydrochloric acid and inflammation that leads to formation of ulcers |