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Physio 2011 Spring

HIV

Question	Answer
HIV	Human Immunodeficiency Virus
AIDS 2	-Acquired Immunodeficiency Syndrome -Disease of HIV
Define bacteria	-Able to reproduce independently, so living organism -Snsitive to anti biotic
Define Virus	-not living organism -Require host cell -Anti-bio does not work
STD is Virus or Bacterial infection?	Bacteria Infection
2 STD disease	-Syphilis -Gonorrhea
Syphilis	Bacterium; Treponema pallidum
Gonorrhea	Bacterium; Neisseria gonorrhoeae
Examples of DNA containing viruses	-Herpes -Small pox -Hepatitis B -Adenovirus
Do viruses have organelle?	NO
Which one is STD? -Herpes -Small pox -Hepatitis B -Adenovirus	Herpes
Which one attack lung cell? -Herpes -Small pox -Hepatitis B -Adenovirus	Adenovirus
Examples of RNA containing viruses	-Hepatitis A&C -Rabies -Ebola -Measles -Mumps -Polio -HIV
Define Retro-vial Replication	Conversion of host cell to DNA
Are all RNA containing virus Retro-virus?	NO
Define reverse transcription	RNA from HIV virus to Viral DNA
Explain Retro-vial Replication	p.2
What is the primary host cell of HIV?	Lymphocytes (WBC)
2 types of Lymphocytes	B & T
2 Types of T-Lymphocytes	-Cytotoxic T-cell -Helper T cell
What is the primary target of HIV?	Helper T cell [infection of T cell cause AIDS]
The name of the receptor of Helper T cells	CD 4
Reverse transcriptase	Enzyme that convert RNA to DNA
Integrase	Retro-viral integrase (IN) is an enzyme produced by a retrovirus (such as HIV) that enables its genetic material to be integrated into the DNA of the infected cell.
Incubation	潜伏
Define pro-virus	DNA sequence that originated through the process of transcription and integrated human genome
Latent	inactive
Lytic	activated
Reverse transcriptase is also called?	Error- Pione
2 Co-receptors	CCR5, CXCR4
Helper cell attaches to ?	Gp 120
3 HIV gene of pro-virus	env, gag, pol
Env gene	Responsible for glyco protein on surface
Gag gene	Responsible for protein in the capsle
Pol gene	Responsible for one of 3 different enzymes
How does virus remake itself?	Carry the gene with it that can reproduce the structure of the enzyme, shell, glycoprotein
Define budding	-Virus is being released from cell -Virus particle surround themselves with a layer of host cell membrane & bud off from the surface fo the host cell
Non-human primate	Simian
Virus that is found in animals, Chimpanzee	Simian immune deficiency virus (SIV cpz)
Simian virus from Pan troglodytes troglodytes is almost identical to ?	HIV 1
Simian virus from Sooty mangabey monkey is corresponds to ?	HIV 2
When proviral DNA is activated, it is called	Lytic stage
When proviral DNA is stored, it is called	Lysogenic stage
Steps of infection 4	1.Vral RNA 2.Infects Helper T-cell 3.Integrates into host DNA 4.Proviral DNA
CRF's, Recombination	process by which a molecule of nucleic acid (usually DNA, but can also be RNA) is broken and then joined to a different one.

Created by: MikiI on 2011-05-29

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Physio 2011 Spring

HIV