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Physio 2011 Spring
HIV
| Question | Answer |
|---|---|
| HIV | Human Immunodeficiency Virus |
| AIDS 2 | -Acquired Immunodeficiency Syndrome -Disease of HIV |
| Define bacteria | -Able to reproduce independently, so living organism -Snsitive to anti biotic |
| Define Virus | -not living organism -Require host cell -Anti-bio does not work |
| STD is Virus or Bacterial infection? | Bacteria Infection |
| 2 STD disease | -Syphilis -Gonorrhea |
| Syphilis | Bacterium; Treponema pallidum |
| Gonorrhea | Bacterium; Neisseria gonorrhoeae |
| Examples of DNA containing viruses | -Herpes -Small pox -Hepatitis B -Adenovirus |
| Do viruses have organelle? | NO |
| Which one is STD? -Herpes -Small pox -Hepatitis B -Adenovirus | Herpes |
| Which one attack lung cell? -Herpes -Small pox -Hepatitis B -Adenovirus | Adenovirus |
| Examples of RNA containing viruses | -Hepatitis A&C -Rabies -Ebola -Measles -Mumps -Polio -HIV |
| Define Retro-vial Replication | Conversion of host cell to DNA |
| Are all RNA containing virus Retro-virus? | NO |
| Define reverse transcription | RNA from HIV virus to Viral DNA |
| Explain Retro-vial Replication | p.2 |
| What is the primary host cell of HIV? | Lymphocytes (WBC) |
| 2 types of Lymphocytes | B & T |
| 2 Types of T-Lymphocytes | -Cytotoxic T-cell -Helper T cell |
| What is the primary target of HIV? | Helper T cell [infection of T cell cause AIDS] |
| The name of the receptor of Helper T cells | CD 4 |
| Reverse transcriptase | Enzyme that convert RNA to DNA |
| Integrase | Retro-viral integrase (IN) is an enzyme produced by a retrovirus (such as HIV) that enables its genetic material to be integrated into the DNA of the infected cell. |
| Incubation | 潜伏 |
| Define pro-virus | DNA sequence that originated through the process of transcription and integrated human genome |
| Latent | inactive |
| Lytic | activated |
| Reverse transcriptase is also called? | Error- Pione |
| 2 Co-receptors | CCR5, CXCR4 |
| Helper cell attaches to ? | Gp 120 |
| 3 HIV gene of pro-virus | env, gag, pol |
| Env gene | Responsible for glyco protein on surface |
| Gag gene | Responsible for protein in the capsle |
| Pol gene | Responsible for one of 3 different enzymes |
| How does virus remake itself? | Carry the gene with it that can reproduce the structure of the enzyme, shell, glycoprotein |
| Define budding | -Virus is being released from cell -Virus particle surround themselves with a layer of host cell membrane & bud off from the surface fo the host cell |
| Non-human primate | Simian |
| Virus that is found in animals, Chimpanzee | Simian immune deficiency virus (SIV cpz) |
| Simian virus from Pan troglodytes troglodytes is almost identical to ? | HIV 1 |
| Simian virus from Sooty mangabey monkey is corresponds to ? | HIV 2 |
| When proviral DNA is activated, it is called | Lytic stage |
| When proviral DNA is stored, it is called | Lysogenic stage |
| Steps of infection 4 | 1.Vral RNA 2.Infects Helper T-cell 3.Integrates into host DNA 4.Proviral DNA |
| CRF's, Recombination | process by which a molecule of nucleic acid (usually DNA, but can also be RNA) is broken and then joined to a different one. |
Created by:
MikiI