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pain neurophysiology
therapeutic mod pain neuro
| Question | Answer |
|---|---|
| Nerve Types | Mylelinated, unmylelinated |
| Mylelinated | Schwann cells form the myelin sheath around the axon of peripheral nerves Olgiodendrocytes form myelin sheath around the axons of the CNS NOR propagates the AP along the axon |
| Nodes of Ranvier | increase speed of ocnduction only on mylelinated nerve cells propagate the AP along the axon |
| Unmylelinated | No schawnn cells, olgiodendrocytes or NOR slower conduction velocities |
| Nerve classifications | Efferent, Afferent |
| Efferent pathways | Motor-A alpha EAT MOTOR NEURON DOES NOT INNERVATE THE SAME DUE TO THE FUNCTION(fine motor control has less then like back where the power is headed) |
| Motor unit | alpha motor neuron and all the muscle fibers it innervates (efferent pathways) |
| Afferent | Sensory-a beta, a delta, |
| What type of nerve fiber is the easiest to innervate | large diameter fibers-have faster nerve conduction as well, A delta |
| A beta | located in the skin sensitive to touch and vibration |
| A delta | located in the skin sensitive to touch and vibration |
| C | Muscle and skin sensetive to pain touch, pressure vibration and temperature |
| Resting membrane potential | the voltage difference between the inside and outside of a cell (-60 to 90 mv) + charge on the outside of the cm due to increase Na - charge on the inside of the cm due to increased K+ Cl is in high concentration on the outside of CM |
| What maintains cell gradient and how? | NA/K pump maintains cell gradient by pumping 3 Na out and 2K in which places a positive charge on the outside of the cell membrane |
| Resting Membrane Potential | Depolarization, repolarization, hyperpolarization |
| Depolarization | inside the cell becomes less negative |
| Repolarization | cell membrane becoming more negative, closer to the RMP |
| Hyperpolarization | cell membrain more negative than resting state |
| Action potential | CM becomes permeable to a + charge causing a DP of the membrane,inside of the cell + to outside /\ in Na gradient then increases K gradient, a charge seperation across the membrane causes an AP to a + point K restores itself to a more - state causing |
| Absolute refractory period | the basis of the absolute refractory period Na channels actually have 3 voltage gated configurations |
| Relative Refractory period | Basis of the relative refractory period: The K+ over shoot K+ channels close near the RP Since the K+ changnels are slower, the membrane potential overshoots the RP about -80 mv near the K+ |
| Na channels 3 volaged gated configurations | Closed(at rest) Open(during AP) Inactive or refractor(just after an AP) |
| Closed configuration for NA channels | ions cannot pass ready to open |
| Open configuration for Na channels | Ions can pass through during an action potential |
| Inactive or refractory configuration of Na Channels | ions cannot pass will not open |
Created by:
jwebst1
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