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Pathophysiology Ch 8
Ch 8 Stress & Disease
Question | Answer |
---|---|
Define Stress. | The state of affairs arising when a person relates to (i.e., interacts or transacts with) situations in a certain way. |
What are the 3 structural changes in rats subjected repeatdly to noxious stimuli (stressors)? | 1. Enlargement of cortex of adrenal gland 2. Atrophy of the thymus gland & other lymphoid tissues 3. Gastointestinal ulceration. |
What is GAS? (General Adaptive Syndrome) | A nonspecific physiologic response to any long-term stressor. |
What are the 3 stages of the General Adaptive Syndrome? | 1. The Alarm Stage-(triggers sympathetic nervous system, ie. body's defenses of fight or flight.) 2. The Stage of Resistance/Adaptation (Mobilization contributes to fight or flight) 3. The Stage of Exhaustion (Impaired Immune Response |
True or False? Stress can produce both a reactive & anticipatory responses to pschologic stressors? | True |
What is a stressor? | A demand that exceeds a person's coping abilities thereby resulting in reactions such as disturbances of cognition, emotion, and behavior that can adverse affect well-being. |
True or Fasle? Cortisol supresses the inflamatory response? | True |
Define Psychoneuroimmmunology. (PNI) | The study of how the consciusness, brain & spinal cord, and body's defense against external infection and abnormal cell division interact. |
What happens in the Alarm stage of GAS? | Increased sympathetic activity |
True or False? Glucocorticoids whould be highest during the stage of Resistance? | True. |
CRF is released by the hypothalamus? | True. |
True or Fasle? Stressors are the same for all individuals? | False. (Stessors are different for all individuals.) |
True or False? Heredity, past experience, & diet are all stimuli that may be stressors for an individual? | True. |
True or False? Cortisol increases protein catabolism? | True. |
In response to stress, the adrenal cortex secrets ___________and ___________. | cortisol and aldosterone. |
True or Fasle? Increased heart rate, a rise in epinephrine levels, and changes in breathing patterns are all results of a severe stress. | True. |
What are Corticoids? | They are secreted by the adrenal cortex in response to stress. |
True or False? Anticipatory response occurs when the body mounts a physiologic response in anticipation of disruption of homeostasis. | True. |
True or False? Reactive response is a psychologic response derived from psysiologic stress? | True. |
True or False? Psychologic stress may cause or exacerbate several diseases such as cardiovascular, cancer, and infectious diseases. | True. |
True or False? Endorphins cause pain. | False. (Endorphins relieve pain.) |
True or False? Testosterone causes immunosuppression. | True. |
True or False? Somatotropin is supressed by chronic stress. | True. |
True or False? Oxytocin has antistress properties. | True. |
True or False? Prolonged stress leads to suppression of growth hormone. | True. |
True or False? IL-1 is produced by macrophages and stimulates the release of Corticotropin-releasing factor (CRF). | True. |
True or False? Corticotropin-releasing factor (CRF) is released by the hypothalamus. | True. |
True or False? Coping is the process of managing stressful challenges that tax the individual's resources. | True. |