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DIT 2009 WK 4
Q&A from DIT emailed questions WK 4
Question | Answer |
---|---|
What are the common side effects of beta-blockers? | Impotence, exacerbation of asthma, cardiovascular adverse effects (bradycardia, AV block, CHF), CNS adverse effects (sedation, sleep alterations) |
Which pt populations should use caution when taking beta-blockers? | Caution w/ diabetics due to the blockage of adrenergic symptoms w/ hypoglycemia |
What are the signs of right-sided heart failure? | Hepatomegaly (nutmeg liver), ankle/sacral edema, jugular venous distention |
What are the signs of left-sided heart failure? | Dyspnea on exertion, cardiac dilation, pulmonary edema/paroxysmal nocturnal dyspnea, orthopnea |
What asthma medication is the inhaled treatment of choice for chronic asthma? | Corticosteroids: Prednisone |
What asthma medication is the inhaled treatment of choice for acute exacerbations | Albuterol |
What asthma medication is known to have a narrow therapeutic index, used as drug of last resort? | Theophylline (Methylxanthines) |
What asthma medication blocks the conversion of arachidonic acid to leukotriene? | Zileuton |
What asthma medication inhibits mast cell release of mediators, used for prophylaxis only? | Cromolyn |
What asthma medication is inhaled and blocks muscarinic receptors? | Ipratropium |
What asthma medication is inhaled and is a long-acting beta-agonist? | Salmeterol |
What asthma medication blocks leukotriene receptors? | Motelukast, Zafirlukast |
What bacterium causes leprosy (AKA Hansen’s disease? | Mycobacterium leprae |
What part of the body is infected in Hansen's Dz? | Skin and superficial nerves infected |
What animal is a reservoir for leprosy in the US? | Armadillos |
What are the symptoms of Kluver-Bucy syndrome? | Hyperorality, hypersexuality, disinhibited behavior |
What area of the brain is damaged in Kluver-Bucy syndrome? | Amygdala (bilateral) |
Why should a “Hot T-Bone stEAk” come to mind when someone asks you about interleukins? | - 1–H: fever, 2–T: T cell stimulation, 3–B: Bone marrow stimulation, 4–E: IgE & IgG, 5–A: IgA & Eosinophils |
Leading causes of death in ages 1-14 | Injuries, cancer, congenital anomalies, homicide, heart disease |
Leading causes of death in ages 15-24 | Injuries, homicide, suicide, cancer, heart disease |
What are the side effects of neuroleptic toxicity | Extrapyramidal system (EPS) side effects, endocrine side effects, antimuscarinic side effects |
In neuroleptic toxicity, describe acute dystonia | 4 hrs – muscle spasm, stiffness, oculogyric crisis |
In neuroleptic toxicity, describe Akinesia | 4 d – parkinsonian symptoms |
In neuroleptic toxicity, describe Akathisia | 4 wk – restlessness |
In neuroleptic toxicity, describe Tardative dyskinesia | 4 mo – stereotypic oral-facial movements due to long term antipsychotic use, often irreversible |
What is the composition of a nucleosome? | Core histones: H2A, H2B, H3, H4 |
Which histone ties nucleosomes together? | H1 (30nm fiber) |
What types of preventive services are needed in Diabetics? | Eye, foot exams; urine tests, flu/pneumo vaccine, daily glc |
What types of preventive services are needed in drug abusers? | Hepatitis immunizations; HIV, TB tests |
What types of preventive services are needed in alcoholics? | Influenza, pneumococcal immunizations; TB test, Hep A & B vaccines |
What types of preventive services are needed in high risk sexual behavior patients? | HIV, hepatitis B, syphilis, gonorrhea, Chlamydia tests, pap smear |
What are the causes of normocytic, normochromic anemia? | • Acute hemorrhage, enzyme defects (G6PD deficiency, PK deficiency), RBC membrane defects (hereditary spherocytosis), BM disorders (aplastic anemia, leukemia), Hemoglobinopathies (sickle cell), Autoimmune hemolytic anemia, Anemia of chronic dz |
What 5 classes of medications are used to treat glaucoma? | • Alpha-agonists, Beta-blockers, Cholinomimetics, Diuretics, Prostaglandin (PGF2alpha) |
What infections are caused by Chlamydiae? | -C. trachomatis: Reactive arthritis, conjunctivitis, nongonococcal urethritis and PID -C. pneumonia and C. psittaci: atypical pneumonia |
What is the treatment for most Chlamydia infections? | Erythromycin or tetracycline |
What are the characteristics of thoracic outlet syndrome? | • Atrophy of thenar and hypothenar eminences, atrophy of the interosseous muscles, sensory deficits on the medial side of the forearm and hand, disappearance of the radial pulse upon moving the head toward the opposite side |
What abnormal lab values would lead you to suspect alcoholic hepatitis? | AST > ALT |
What are the most common locations for atherosclerosis? | Abdominal aorta > coronary artery > popliteal artery > carotid artery |
What vitamin deficiencies would you expect to see in a pt with a malabsorption syndrome such as cystic fibrosis or celiac sprue? | Fat soluble vit deficiency - A, D, E, K |
What types of pancreatic tumors are often seen in MEN type I? | Pancreatic endocrine tumors: Zollinger-Ellison syndrome, insulinomas, VIPomas, glucagonomas (rare) |
Nerve innervation for tongue sensation of the anterior 2/3's | V3 (1st Arch) |
Nerve innervation for tongue sensation of the posterior 1/3 | IX (3rd and 4th Arch) |
Nerve innervation for tongue sensation of the posterior root | X |
Nerve innervation for tongue taste in the anterior 2/3's | VII (Chrodatympani) |
Nerve innervation for tongue taste in the posterior 1/3 | IX |
Nerve innervation for tongue taste in the posterior root, taste buds of larynx and upper esophagus | X |
Nerve innervation for tongue motor (except pataloglossus m) | XII |
Nerve innervation for tongue pataloglossus muscle | X |
What is the classic presenting symptom in a pt with Lyme disease? | Erythema chronicum migrans: expanding “bull’s eye” red rash w/ central clearing |