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Pharmacology wk 6
Pharmacology wk 6 Woodrow
Question | Answer |
---|---|
agglutination | mismatching of blood groups, sometimes caused by tranfusion of wrong blood type |
albumin | proteins in the blood; plays a role in maintaining osmotic pressure and water balance between blood and tissues |
lymphocytes | involved in the production of antibodies and play a role in immune response; smallest of leukocytes |
clot | what is formed at the site of injury by fibrin to stop bleeding |
complement | a globulin; important in the immune response of the body |
embolism | an embolus becomes lodged and causes cut off of circulation |
ABO blood group | the grouping of blood types, according to major antigens A and B; there is no O antigen |
embolus | a dislodged bloodclot; is transported through the bloodstream |
erythrocytes | red blood cells; important in transport of oxygen and carbon dioxide in blood |
leukocytes | white blood cells; two subcategories, agranular (nongranular) and granular |
platelets | thrombocytes; produced in red bone marrow from megakaryocytes; disk shaped fragments with a nucleus, range in size; prevent fluid loss resulting by clotting blood |
granular leukocytes | neutrophils, eosinophils, basophils |
agranular leukocytes | monocytes and lymphocytes |
plasma | the fluid component of blood |
globulins | act as transports molecules for hormones, antibodies, complements |
fibrinogen (soluble) | plays a role in the clotting of blood; is converted into insoluble fibrin, forming long threads that act like a net at the site of injury, forming the clot |
other solutes of blood | ions, nutrients, waste products, gases, enzymes and hormones |
hematopoiesis | blood cell formation |
red bone marrow (myeloid tissue) | where blood cell formation occurs |
stem cells (hematocytoblasts) | undifferentiated mesenchymal cells; multi-use cells; formed in the red bone or myeloid tissue |
hemoglobin | red pigmentation of the blood |
heme | pigment containing four iron atoms, combining with oxygen, which gives it a lighter color; the more oxygen, the lighter color |
globin | protein of the blood, makes up hemoglobin |
phagocytosis | eating cells |
lysozyme | destroys certain bacterias |
macrophages | monocytes are the largest leukocyte, leave the blood and enter tissues and increase in size |
eosinophils | combat irritants ie. pollen and allergens, produce antihistamines; can also attack some worm parasites |
basophils | involved in allergic reactions, release heparin histamine and serotonin into tissues |
neutrophils | important for immune defense; respond to tissue destruction from bateria; phagocytise foreign substances and secrete lysozyme |
monocyte | important for immune surveillance; precurser to tissue macrophage |
B lymphocyte | antibody production; precurser to plasma cells |
T lymphocyte | cellular immune response |
megakaryocytes | produce the thrombocytes/platelets in red bone marrow |
thromboplastin | causes a series of reactions that produce prothrombin activators, requiring presence of calcium irons and proteins and phospholipids for repair of damaged tissue |
prothrombin | a plasma protein produced by the liver; second stage of blood clotting; becomes thrombin |
thrombin | what prothrombin becomes in second stage of blood clotting; catalyzes the reaction of fibrinogen into fibrin |
syneresis | clot retraction; the tightening of the fibrin clot so that injured flesh becomes smaller, cutting off the hemorrhage |
fibrinolysis | dissulution of the blood clot |
plaque | a cholesterol containing mass that clogs blood vessels |
thrombosis | clotting in an unbroken blood vessel |
thrombus | the clot in a blood vessel caused by thrombosis |
infarction | when tissue is killed due to embolism or thrombosis |
RH blood group | antigen D, causing negative or positive inherited traits in blood |
erythroblastosis fetalis | hemolytic disease of newborns; blood type didn't match mother's blood type causing brain damage and anemia, resulting in death |