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WVSOM -- immunmo
WVSOM -- Combank/Kaplan -- CD/IL/Complement
Question | Answer |
---|---|
C5b-9 | MAC |
C5a | Neutrophil chemotaxis |
C3b | opsonization protein |
What works with C3b to opsonize bacteria? | IgG |
C1,C2,C3,C4 | classical pathway that are involved in viral neutralization |
T Cell, thymocytes, NK cells. Adhesion molecule | CD2 |
T Cells and thymocytes, Signal transduction by TCR | CD3 |
Coreceptor for MHC class I-restricted T cells | CD8 |
LPS receptor on monocytes, macrophages and granulocytes | CD14 |
Fc receptor found on NK cells, marcrophages, neutrophils for opsonization and ADCC | CD16 |
Cell adhesion molecule in leukocytes | CD18 |
Coreceptors for b-Cell activation | CD19/21 |
Unknown role in B-cell activation | CD20 |
Epstein Barr Virus receptor | CD21 |
T cell receptor for costiulatory molecule B7 | CD28 |
Cell-cell adhesion, binds L-selectin and found on precursors of hematopoietic cells, endothelial cells in HEV | CD34 |
Leukocyte common antigen. critical role in receptor mediated singaling of T and B cells | CD45 |
NK cells | CD56 |
Coreceptor for TCR-MHC II interaction | CD4 |
CD receptor for HIV | CD4 |
costimulates activation of TH cells | IL-1 |
promotoes maturaion and clonal expansion of B cells | IL-1 |
Enhances activity of NK cells | IL-1 |
Chemotactiacally attracts macrophages and neutrophils | IL-1 |
Induces fever in hypothalamus | IL-1 |
Induces synthesis of acute-phase proteins in hepatocytes | IL-1 and IL-6 |
induces proliferation and enhances activity of antigen primed TH and CTLs | IL-2 |
Supports growth and differentiation of hematopoietic cells | IL-3 |
Costimulates antigen-primed B Cells | IL-4 |
Stimulates proliferaion and differentiataion,as well as inducing class switch to IgG1 and IgE | IL-4 |
Stimulates proliferation and differentiation and induces class switch to IgA in activated B cells | IL-5 |
Promotes terminal differentiation into plasma cells | IL-6 |
Stimulates Ab secrion by plasma cells | IL-6 |
Induces differentiation into progenitor B and T cells in Lymphoid stem cells | IL-7 |
Chemokine to indicue adherence of neutrophils to endothelium and extravasion into tissues | IL-8 |
suppresses cytokine production by TH1 cells | IL-10 |
Acts syunergistically with IL-2 to induce differentiaion in to CTL | IL-12 |
Inhibits viral replication secreted by leukocytes | Interferon alpha |
Inhibits viral replication secreted by fibroblasts | Interferon beta |
Enhances activity of macrophages | interferon gamma |
increases expression of class I MHC molecules | IFN-gamma |
Induces class switch to IgG2a, blocks IL-4-induced class switch to IgE and IgG1 in proliferating B cells | IFN-gamma |
inhibits proliferation of TH2 cells | IFN-gamma |
Induces class switch to IgA | TGF-Beta |
Cytotoxic effect on tumor cells and induces cytokine secretion causing cachexia of chronic inflamation | TNF-alpha |
cytotoxic effects as well as enhancing phagocytic activity | TNF-beta |
Found on all nucleated cells of the body | MHC I |
found on all APCs | MHCII |