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GI 1,2

GenericBrandCategoryIndicationSide effects
Dicyclomine (PO) Bentyl Anticholinergic; Antispasmodic IBS drowsiness, blurred vision, dizziness Notes: Caution in CV disease, hepatic/ renal impairment, & hyperthyroidism
Lubiprostone (PO) Amitiza Chloride channel activator IBS w/ constipation, chronic constipation, opioid-induced constipation nausea, headache, dyspnea Notes: CI in GI obstruction
Dexamethasone (PO, IV) DexPak, DoubleDex Corticosteroid Inflammatory diseases, cerebral edema hyperglycemia, increased appetite w/ weight gain, depression, irritability, osteoporosis (chronic use), Cushing's syndrome (chronic use) Notes: risk of adrenal suppression w/ prolonged use
Methylprednisolone (PO, IV) Medrol Corticosteroid Inflammatory diseases, COPD/ asthma exacerbation, acute gout hyperglycemia, increased appetite w/ weight gain, depression, irritability, osteoporosis (chronic use), Cushing's syndrome (chronic use) Notes: risk of adrenal suppression w/ prolonged use
Prednisolone (PO) Orapred Corticosteroid Inflammatory diseases, COPD/ asthma exacerbation, acute gout hyperglycemia, increased appetite w/ weight gain, depression, irritability, osteoporosis (chronic use), Cushing's syndrome (chronic use) Notes: risk of adrenal suppression w/ prolonged use
Prednisone (PO) Deltasone Corticosteroid Inflammatory diseases, COPD/ asthma exacerbation, acute gout hyperglycemia, increased appetite w/ weight gain, depression, irritability, osteoporosis (chronic use), Cushing's syndrome (chronic use) Notes: risk of adrenal suppression w/ prolonged use
Hydrocortisone (IV, topical) Topical: Cortisone, Cortaid IV: Solu-Cortef Corticosteroid Topical: Inflammation, rash | PO/IV: Acute illness, adrenal insufficiency hyperglycemia, increased appetite w/ weight gain, depression, irritability, osteoporosis (chronic use), Cushing's syndrome (chronic use) Notes: risk of adrenal suppression w/ prolonged use
Metoclopramide (PO, IV) Reglan Dopamine (D2) antagonist Gastroparesis, GERD, n/v drowsiness, dystonia, akathisia, EPS, QTc prolongation, diarrhea Warnings: may cause tardive dyskinesia
Prochlorperazine (PO, PR, IM, IV) Compazine Dopamine (D2) antagonist n/v drowsiness, dizziness, xerostomia, blurred vision, constipation, QTc prolongation Warnings: increased risk of death in elderly pts w/ dementia-related psychosis Notes: do not admin IV push
Ondansetron (PO, IV) Zofran, Zofran ODT Selective serotonin (5-HT3) antagonist n/v headache, fatigue, constipation, QTc prolongation
Promethazine (PO, IM, IV, PR) Phenergan Histamine (H1) blocker Motion sickness, n/v drowsiness, dry mouth, blurred vision, QTc prolong Warnings: potential fatal respiratory depression in patients < 2 yo; injection can cause peripheral extravasation (preferred parenteral route IM)
Lactulose (PO) Enulose, Constulose Laxative Constipation, hepatic encephalopathy abdominal cramps/ distention, diarrhea, flatulence
Diphenoxylate and atropine (PO) Lomotil Antidiarrheal Diarrhea nausea, confusion, drowsiness, dizziness, xerostomia, tachycardia, urinary retention
Famotidine (PO, IV) Pepcid Histamine (H2) blocker GERD, erosive esophagitis, SUP headache, constipation, diarrhea, mental status changes
Sucralfate (PO) Carafate Gastrointestinal protectant PUD constipation, bezoar formation
Dexlansoprazole (PO) Dexilant PPI GERD, PUD, erosive esophagitis, SUP abdominal pain, nausea, diarrhea, bone fracture, vitamin B12 deficiency, hypomagnesemia Warnings: increased risk of Clostridioides difficile infection
Esomeprazole (PO, IV) Nexium PPI GERD, PUD, erosive esophagitis, SUP abdominal pain, nausea, diarrhea, bone fracture, vitamin B12 deficiency, hypomagnesemia Warnings: increased risk of Clostridioides difficile infection
Lansoprazole (PO) Prevacid PPI GERD, PUD, erosive esophagitis, SUP abdominal pain, nausea, diarrhea, bone fracture, vitamin B12 deficiency, hypomagnesemia Warnings: increased risk of Clostridioides difficile infection
Omeprazole (PO) Prilosec PPI GERD, PUD, erosive esophagitis, SUP abdominal pain, nausea, diarrhea, bone fracture, vitamin B12 deficiency, hypomagnesemia Warnings: increased risk of Clostridioides difficile infection
Pantoprazole (PO, IV) Protonix PPI GERD, PUD, erosive esophagitis, SUP abdominal pain, nausea, diarrhea, bone fracture, vitamin B12 deficiency, hypomagnesemia Warnings: increased risk of Clostridioides difficile infection
Created by: Aware19
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