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Pain, Hema & Onc 2
Brand | Generic | Category | Indication | Side Effects |
---|---|---|---|---|
Methotrexate (PO) | Trexall | Antimetabolite (folic acid antagonist) | Rheumatoid arthritis, Crohn’s Disease, psoriasis, various hematologic & solid tumors | stomatitis, diarrhea, n/v, thrombocytopenia, leukopenia, increased hepatic transaminases, pulm fibrosis (rare) potential fetal death/ abnormalities (avoid in pregnancy); severe/ fatal bone marrow suppression, aplastic anemia, & GI toxicity w/ NSAID use |
Anastrozole (PO) | Arimidex | Aromatase inhibitor | Hormone receptor positive breast cancer | fatigue, rash, flushing, hot flashes, arthralgia, n/v, HTN, peripheral edema, osteoporosis Notes: CV side effects hypercholesterolemia, CAD); fetal toxicity (CI in pregnancy) |
Phentermine (PO) | Adipex-P | CNS stimulant | Obesity | HTN, nausea, dizziness, xerostomia, primary pulm HTN (rare) Notes: only approved for short-term use; CI in pts w/ history of CV disease, drug abuse, pregnancy, hyperthyroidism, or w/n 14 days of MAOI inhibitor therapy |
Ferrous sulfate (PO) | FeroSul, SlowFe | Iron supplement | Iron deficiency anemia | nausea, stomach upset, constipation (dose-related), dark & tarry stools Warning: Accidental iron overdose = leading cause of fatal poisoning in kids <6 yo |
Cyanocobalamin (vitamin B12) (PO, IM, SL, intranasal) | n/a | Water-soluble vitamin | Vitamin B12 deficiency (manifests as macrocytic anemia) | no major side effects |
Folic acid (PO) | n/a | Water-soluble vitamin | Folic acid deficiency (manifests as macrocytic anemia), prevention of neural tube defects in pregnancy | no major side effects |