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Pneumonia
Term 1 | Term 2 |
---|---|
CAP CURB-65 Score of 0-1 | CURB-65= Outpatient w/ PO ABX |
CAP CURB-65 Score of 2 | CURB-65= Outpatient/ inpatient PO or IV ABX |
CAP CURB-65 Score of 3 | CURB-65= Inpatient w/ IV ABX |
CAP CURB-65 Score of 4-5 | CURB-65= Inpatient ICU x/ IV ABX |
TX for CAP CURB-65 score of 0-1 or PSI </=90 with NO comorbidities | PO Amoxicillin, doxycycline, Azithromycin (if resistance <25%) |
TX for CAP CURB-65 score of 0-1 or PSI </=90 WITH comorbidities | PO: (Augmentin OR Cephalosporin) + (Azithromycin OR Doxycycline) -OR- Levofloxacin OR Moxifloxacin (Renal adjustment needed) |
TX for CAP CURB-65 Score of 2+ or PSI >/=91 + NON Severe | IV: Beta lactam + Azithromycin -OR- Levofloxacin or moxifloxacin -OR- beta lactam + doxycycline |
TX for CAP CURB-65 Score of 2+ or PSI >/=91 + Severe + MRSA RISK | IV: Beta lactam + Azithromycin -OR- Beta Lactam + Levofloxacin or moxifloxacin -AND- Vanco or linezolid |
Criteria for a 5 day minimum tx for CAP | Afebrile for >/= 48-72 hours meets 5-6 of the following: HR ≤100 beats/min RR ≤ 24 breaths/min SBP ≥ 90 mmHg O2 sat ≥ 90% on RA Tolerate PO intake Baseline mental status |
Criteria for a 7 day max tx for CAP | Initial ABX lacked coverage immunocompromised pt if pt has a current other infection or complication |
CAP CURB-65 score of 0-1 or PSI </=90 with NO comorbidities MC pathogens | Strep pneumoniae, atypical, viral |
CAP CURB-65 score of 0-1 or PSI </=90 WITH comorbidities MC pathogens | Strep pneumoniae, H. flu, M catarrhalis, Staph aureus, Pseudomonas |
CAP CURB-65 Score of 2+ or PSI >/=91 + NON Severe MC pathogens | Strep pneumoniae, atypical, viral |
TX for CAP CURB-65 Score of 2+ or PSI >/=91 + Severe MC pathogens | Strep pneumoniae, H. flu, M catarrhalis, Staph aureus, Pseudomonas, Legionella |
HAP caused by a hospitalization < 5 days MC causes | Strep pneumoniae, H. flu, Staph aureus, E coli, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas |
HAP caused by a hospitalization >/= 5 days OR MDR risk MC causes | Staph aureus and ESKAPE (E coli, Serratia marcescens, Klebsiella pneumoniae, Acinetobacter baumannii, pseudomonas, Enterobacter) |
MRSA and other MDR Risk factor (pseudomonas) | ABX within 90 days |
Tx for HAP/ VAP | Pip/ tazo, cefepime, levofloxacin, impipenem, or metropenem x 7days |
TX for HAP/ VAP IF pseudomonas of Gram- MDR is suspected | Pip/ tazo, cefepime, ceftazidime, aztreonam, impipenem, or meropenem -AND- cirpofloxacin, levofloxacon, or tobramycin x 7 days |
TX for HAP/ VAP IF pseudomonas of Gram- MDR and MRSA MDR is suspected | Pip/ tazo, cefepime, ceftazidime, aztreonam, impipenem, or meropenem -AND- cirpofloxacin, levofloxacon, or tobramycin -AND- vancomycin or linezolid x 7 days |
TX for CAP CURB-65 Score of 2+ or PSI >/=91 + Severe | IV: Beta lactam + Azithromycin -OR- Beta Lactam + Levofloxacin or moxifloxacin |