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Dysmorphology

FH and FAS

QuestionAnswer
FAS features Microcephaly, short stature or small; sleep problems; heart problems; vision problems; learning disabilities; behavioral problems; hearing problems; coordination problems
Major features of FAS (face) Short palpebral fissures; flat midface; smooth philtrum; thin upper lip; micrognathia
Associated features of FAS (face) Epicanthal folds; flat nasal bridge; short upturned nose
Dx of FAS depends on facial features; evidence of brain dysfunction; pre and post natal growth deficiency in the presence of prenatal alcohol exposure
Therapies for development and behavior should focus on... Sensory/motor/regulatory; attention; communication-language; communication-social; cognitive; achievement; memory; executive functioning; adaptive/social; neurological abnormalities
Fetal Anticonvulsant Syndrome (aka FH) features eyelid ptosis; ocular hypertelorism, inteverted nose, midface hypoplasia; anteverted nose, hearing loss/impairment; nail hypoplasia; growth retardation; hypospadias; renal malformations; inguinal hernia;
FH has abnormalities of... 1. Growth 2. Performance 3. Craniofacial 4. Limbs 5. Other (short neck, widely spaced nipples; rib anomalies; low-set hairline; simian crease; inguinal hernias; etc.)
Natural Hx of FH Infants present with Failure-to-thrive during early postnatal month; growth of nails and distal pahalange; mental deficiency of greatest concern
Created by: KChatham
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