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Quiz 1

Top 200 Drugs

GenericBrandTherapeutic ClassIndicationAEsPearls
Carbamazepine Tegretol XR, Carbatrol ER, Equetro ER Anticonvulsant Bipolar disorder, seizures, neuropathic pain SJS, TENS, n/v, dizziness HLA-B*1502 (+) should avoid (high risk for SJS and TEN), induces own metabolism (autoinduction)
Divalproex Sodium Depakote (ER) Anticonvulsant/bipolar agent Bipolar disorder, focal and generalized onset seizures, migraine prophylaxis Suicidal ideation, thrombocytopenia, drowsiness, tremor BBW for fetal risk, avoid in pregnancy, ok for breast feeding
Gabapentin Neurontin Anticonvulsant/bipolar agent Postherpetic neuralgia, seizures CNS depression, respiratory depression, drowsiness, dizziness, suicidal ideation Not controlled but monitored by WI PDMP, avoid alcohol (CNS depression), avoid pregabalin
Lamotragine Lamictal (XR, ODT, CD) Anticonvulsant & analgesic Bipolar I disorder, seizures, focal and generalized seizures DRESS, skin reactions, weight gain, suicidal ideation High skin rash risk if stopped for >5 days and didn't restart titration or if coadministration with divalproex
Levetiracetam Keppra Anticonvulsant & analgesic Seizures CNS depression, suicidal thoughts, increased BP, drowsiness, dermatologic reactions Unusual changes in mood or behavior
Oxacarbazepine Trileptal, Oxtellar XR Anticonvulsant Seizures Agranulocytosis, hyponatremia, nystagmus, vomiting, hepatic dysfunction ER on empty stomach, avoid carbamazepine d/t cross-reactive rash
Phenobarbital N/A Anticonvulsant - barbiturate N/A (off-label for epilepsy and sedation) Somnolence, syncope, hallucinations, barbiturate withdrawal Report withdrawal s/sx w/dose reduction or d/c
Phenytoin Sodium Dilantin Anticonvulsant Seizures, status epilepticus Gingival hyperplasia, cardiac arrhythmia, acute hepatic failures, nausea, hirsutism Peds @ high gingival hyperplasia risk, vesicant so needs proper infusion needle handling
Pregabalin Lyrica Anticonvulsant & analgesic DPN, fibro, neuropathic pain, seizures CNS depression, respiratory depression, drowsiness, dizziness, suicidal ideation C-V, avoid alcohol (CNS depression)
Topiramate Topamax, Trokendi XR Anticonvulsant Seizures, migraines Cognitive dysfunction, fatigue, metabolic acidosis, ocular effects, suicidal thoughts Weight loss, more cognitive ADRs
Created by: NKK2000
Popular Pharmacology sets

 

 



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