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HIV Info & Laboratory Testing

When is HIV considered the most infectious? WINDOW PERIOD
When does HIV RNA become detectable? p24 antigen? when do symptoms begin? when is ELISA effective? HIV RNA (1 week); p24 (2 weeks, dropping off after 5 weeks), ELISA (3 weeks)
When does p24 antigen begin to decrease in titer? 5 weeks
what is the first marker to appear in the HIV infection? p24 antigenweeks after exposure
when does IgM antibody show up? 3-5 weeks, dropping a little after IgG is made (to envelope and core)
explain the titer profile of HIV over the course of the infection. p24 (2-4wks), IgM Ab(3-5wks), p24 drops off as IgM peaks, IgG ENV rises, then IgG CORE rises, IgM falls, IgG CORE declines, p24 rises again, CORE IgG drops off. ENV IgG is elevated for WAY LONGER
Created by: HSF2