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obesity

obesity medications

namecommon namesside effectsdosecontraindicationsDrug classaction
meformin common brands: glucophage, riomet, glumetza, glucophage xr, and fortamet diarrhea, nausea, vomiting and flatulence once or twice daily: available immediate release (500mg, 850mg, and 1000mg) and extended release (500mg and 1000mg), Max dose 2500mg/day severe kidney disease (eGFR<30ml/minute/1.73m^2 metabolic acidosis, or diabetic ketoacidosis caution: experiencing muscle aches, abdominal pain; monitor b12 periodically with long term therapy Non-sulfonylureas diabetes patients. It reduces glucose absorption from the intestines, lowers liver glucose production, and improves insulin sensitivity. Improves insulin sensitivity, decreases blood glucose levels, decreases appetite, decreases body fat
Ozempic Semaglutide Nausea, fatigue, HA, dizziness, vomiting, upset stomach, diarrhea, constipation SQ Weekly week 1-4: 0.25mg week 5-8: 0.5mg week 9-12: 1mg week 13 and after: 2mg caution: pancreatitis, and patients on diabetes medicine (insulin, sulfonylurea; Family or person history of medullary thyroid cancer or multiple endocrine neoplasia syndrome; nursing or pregnant women GLP-1 receptor agonist indicated for diabetes; it decreases hunger and increases fullness
Wegovy Semaglutide Nausea, fatigue, HA, dizziness, vomiting, upset stomach, diarrhea, constipation, heartburn SQ Weekly week 1-4: 0.25mg week 5-8: 0.5mg week 9-12: 1mg week 13-16: 1.7mg week 17 and afterward: 2.4mg caution: pancreatitis, and patients on diabetes medicine (insulin, sulfonylurea; Family or person history of medullary thyroid cancer or multiple endocrine neoplasia syndrome; nursing or pregnant women GLP-1 receptor agonist indicated for BMI >/=27 and one additional obesity related condition (sleep apnea, HTN, DM, high cholesterol) or BMI >/= 30; it decreases hunger and increases fullness
Mounjaro tirzepatide Decrease appetite, nausea, diarrhea, vomiting, constipation, dyspepsia GLP-1 receptor agonist and GIP (glucose dependent insulinotropic polypeptide
Saxenda Liraglutide Nausea, fatigue, HA, dizziness, vomiting, upset stomach, diarrhea, constipation SQ Daily week 1: 0.6mg week 2: 1.2mg week 3: 1.8mg week 4: 2.4mg week 5 and afterward: 3.0mg caution: pancreatitis, and patients on diabetes medicine (insulin, sulfonylurea; Family or person history of medullary thyroid cancer or multiple endocrine neoplasia syndrome; nursing or pregnant women GLP-1 receptor agonist indicated for BMI >/=27 and one additional obesity related condition (sleep apnea, HTN, DM, high cholesterol) or BMI >/= 30; it decreases hunger and increases fullness
Zoloft sertraline Nausea, dizziness, drowsiness, dry mouth, loss of appetite, increased sweating, diarrhea, upset stomach, or trouble sleeping may occur may affects the heart rhythm (QT prolongation). antidepressant
Topamax or N Topiramate metallic or flat taste to carbonated beverages, word finding difficulties, numbness and tingling in hands/feet, problems with mood, concentration/attention Take po medication in afternoon; starting dose 25mg. Dose may be titrated 25mg every 2-4 wees. Typical dose 25-100mg/day Kidney stones; glaucoma; Taking topiramate during pregnancy may increase the risk of cleft lip and/or cleft palate, a birth defect that can develop early in pregnancy Carbonic anhydrase inhibitor anticonvulsants for obesity: unknown; Through past studies have shown it may decrease hunger or have a role in how fat is stored in the body Normally used for migraines, seizures
phentermine or Diethylpropion Adipex-P; Lomaira heart palpitations, anxiety, HTN, nausea, dry mouth (xerostomia), dizziness take 8mg table daily tid 30 minutes prior to meal; or 15-37.5mg once daily before breakfast; some cases may administer 18.75mg once to twice daily. patient with history of cardiovascular disease, drug abuse, pregnancy, hyperthyroidism or within 14 days of MAOI inhibitor therapy CNS stimulant; sympathomimetrics weight loss by decreasing appetite
bupropion
victoza
Vyvanse *FDA approved for binge eating disorder LIsdexamfetamine reduces bunge-eating and related obsessions and compulsions
Zepbound tirzepatide GLP-1 receptor agonist and GIP (glucose dependent insulinotropic polypeptide indicated for BMI >/=27 and one additional obesity related condition (sleep apnea, HTN, DM, high cholesterol) or BMI >/= 30; it decreases hunger and increases fullness
Qsymia (phentermine/topiramate)
Contrave (Naltrexone ER/ Bupropion ER)
Plenity
Created by: marlenecornelius
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