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Pharm 2
Fertility Drug therapy
| Question | Answer |
|---|---|
| Which description of clomiphene citrate’s mechanism of action is accurate? | Inhibits estrogen receptors in the hypothalamus and pituitary gland to secrete more FSH and LH to stimulate ovulation |
| Which statement about the pharmacokinetic parameters of testosterone is accurate? | Testosterone undergoes hepatic metabolism and beta-oxidation |
| Which statements about the therapeutic use and pharmacodynamic parameters of clomiphene citrate are accurate? | -The drug’s elimination half-life is 5 to 7 days. -Clomiphene citrate’s duration of action is 30 days. -The drug is indicated for use in women with persistent ovulatory dysfunction to stimulate ovulation. |
| -- | -When administered to women with polycystic ovary syndrome (PCOS) who are on metformin, the success rate of ovulation is increased. |
| Which time frame represents the anticipated elimination half-life of most testosterone products? | 10 to 100 minutes |
| A nurse is caring for a patient who has been prescribed oral methyltestosterone therapy for infertility. This patient also takes warfarin and lisinopril. | -- |
| Which outcome and intervention are recommended to manage a potential drug interaction with methyltestosterone? | Methyltestosterone may increase the effects of warfarin; decrease the dosage of warfarin. |
| Which teaching points would a nurse share with a patient who has diabetes and is initiated on a gel formulation of testosterone? | -The drug can be transferred to others if is not completely dry. -The patient should not abruptly discontinue therapy with testosterone. -The patient should monitor his weight and report any weight gain of more than 5 lbs in a week. |
| -- | The patient should have his testosterone levels monitored within 2 to 4 weeks after starting the drug. |
| A nurse is caring for a patient who has been prescribed clomiphene citrate for infertility. The patient also takes methyldopa for hypertension. | -- |
| Which outcome would a nurse anticipate may come from the drug interaction between methyldopa and clomiphene citrate? | Impaired fertility due to an increase in prolactin |
| Which administration considerations would be given to a nurse who is caring for a patient initiated on clomiphene citrate? | -The dose may be taken with or without food. -The maximum number of sequential cycles of clomiphene citrate is three. -The initial dose of 50 mg once daily and may be increased by 50 mg/day for a second course if ovulation does not occur. |
| -- | -Ovulation typically occurs within 5 to 10 days after the last dose, and intercourse should take place at least every other day. |
| Which patient parameters would a nurse inquire about when a patient returns to have his testosterone levels monitored? | -Weight changes -Mood alterations -Blood glucose readings -Blood pressure changes |
Created by:
Lightnning54
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