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Orange Block 6 & 7
Bisphosphonate, Gout medications, etc.
Question | Answer |
---|---|
Ends in -dronate | Bisphosphonate |
Antiresorptive | Bisphosphonate MOA |
Inhibits Osteoclast activity | Bisphosphonate MOA |
Suppresses bone turnover & bone loss | Bisphosphonate MOA |
Take on a n empty stomach, with a full glass of water, don't lay down for at least 30 minutes after taking, and avoid dairy, iron, and antacids. | Aux labels for Bisphosphonates |
Painful swallowing, heartburn, N/V/D, and can cause damage to the esophagus | Common Adverse Reactions of Bisphosphonates |
alendronate | Fosamax |
10mg tabs - Once daily 70mg tabs - Once weekly | Fosamax |
risedronate | Actonel |
35mg tabs - Once weekly 150mg tabs - Once monthly | Actonel |
allopurinol | Zyloprim |
100mg, 200mg, 300mg tabs Uric acid synthesis inhibitor May take with food Take with glass of water Used to treat gout | Zyloprim |
probenecid | Benuryl |
500mg tabs Uricosuric Take with food Take with water Used to treat gout | Benuryl |
0.6mg tabs Anti-inflammatory Take with water Avoid alcohol Used to treat gout | colchicine |
indomethacin | Indocid |
25mg, 50mg caps NSAID Take with water Take with food Used to treat gout | Indocid |
naproxen | Naprosyn |
250mg, 375mg, 500mg tabs NSAID Take with water Take with food Used to treat gout | Naprosyn |
Used to treat GERD, Ulcers | Prokinetics |
Increased peristalsis Speeds gastric emptying Improves lower esophageal sphincter tone (LES) | MOA of Prokinetics |
Commonly dosed TID before meals and HS | Prokinetics |
metoclopramide | Maxeran |
50mg, 10mg tabs Oral liquid | Maxeran |
domperidone | Motilium |
10mg tabs | Motilium |
Used to treat constipation | Laxatives |
Non-absorbable substances that pull water into lumen Increase stool frequency & consistency | MOA of Osmotic Laxatives |
Increases water & bulk of stool Improves stool consistency Patient must take with lots of water | MOA of Bulk Forming Laxatives |
Increases GI motility | MOA of Stimulant Laxatives |
Commonly dosed PRN | Laxatives |
lactulose | Acilac |
Osmotic laxative Oral liquid 667mg/mL Usually 15-30mL per dose Available OTC | Acilac |
bisacodyl | Dulcolax |
Stimulant Laxative 5mg tabs 5mg, 10mg supps | Dulcolax |
psylium | Metamucil, Mucillium |
Bulk Forming Laxative | Metamucil, Mucillium, Prodiem |
polycarbophil | Prodiem |
sennosides | Senokot |
Stimulant Laxative 8.6mg tabs | Senokot |
Commonly used to treat diarrhea | Anti-diarrheals |
loperamide | Imodium |
2mg tabs Available OTC | Imodium |
diphenoxylate + atropine | Lomotil |
2.5mg diphenoxylate + 0.025mg atropine Narcotic | Lomotil |
docusate sodium | Colace, Soflax |
100mg caps Often dosed 1-2 caps BID-QID | Colace, Soflax |
docusate calcium | Surfak |
240mg caps Often dosed 1-2 caps BID-QID | Surfak |
Commonly used to treat Nausea | Anti-nauseants |
dimenhydrinate | Gravol |
Tablets available OTC Injectable | Gravol |
ondansetron | Zofran |
4mg, 8mg tabs & ODT Injectable Used for severe nausea in chemo patients | Zofran |
doxylamine + pyridoxine hcl | Diclectin |
10mg doxylamine + 10mg pyridoxine hcl tabs Used to treat nausea and emesis in pregnancy | Diclectin |
prochlorperazine | Stemetil |
5mg, 10mg tabs Injectable First gen anti-psychotic primarily used from migraines and nausea associated with chemo | Stemetil |