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Chapter 3
Term | Definition |
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placebo effect | a patients positive expectations about treatment and the care received can positively affect the outcome of therapy |
nocebo effect | negative expectations about therapy and the care received |
placebo | a drug dosage form that has no pharmacologic activity because the dosage form has no active ingredients |
protein binding | drugs that are relatively insoluble are transported in the circulation by being bound to plasma proteins |
metabolites | drugs, which are the products of metabolism |
therapeutic drug monitoring | the measurement of a drugs concentration in biologic fluids to correlate the dosage administered and the level of medicine in the body pharmacologic response. |
tolerance | occurs when a person begins to require a higher dosage of a medication to produce the same effects that a lower dosage once |
drug dependence | also known as "addiction" or "habituation", occurs when a person is unable to control a desire for ingestion of drugs |
physiologic (drug dependence) | which the persons develops withdrawal symptoms if the drug is withdrawn for a certain period |
psychological (dependence) | which the patient is emotionally attached to the drug |
drug accumulation | when a drug accumulate in the body if the next dose is administered before the previously administered dose has been metabolized or excreted |
genetics | the study of how living organisms inherit the characteristics or traits of their ancestors |
genome | the complete package of genetic coding of an organism |
polymorphisms | naturally occurring variations in the structures of genes and instruction that they give to the organisms |
pharmacogenetics | the study which of how drug response may vary in accordance with inherited difference |
teratogens | abnormal development of key tissues (birth defects) |