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Calcium and bones
Drug | MOA/A/E | Considerations |
---|---|---|
Calcium salts | Used for disorders involving calcium/hypocalcemia | no steroids, tetra, fluoro, diuretics, thyroid hormone, phenytoin |
Calcium chloride/Calcium gluconate | Irritation to veins (Gluconate is slightly less) Severe hypocalcemia | push SLOOOOW, warm to body temp, severe bradycardia with Digoxin, watch for extravasation |
Calcitonin salmon | inhibits osteoclasts(break down bones) lowers CA serum levels increases CA excretion | nasal spray (dryness in nares) |
Alendronate | Bisphosphonates inhibits osteoclasts Osteoporosis Esophageal ulcers/Cancer | NO FOOD |
Raloxifene | Similar to estrogen CLOTS!! Fetal Harm | no preggy(test) |
Denosumab | monoclonal antibodies for osteoporosis in post menopausel women and men high risk for fractures |